| Project/Area Number |
22790345
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Human pathology
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 胃癌発癌 / H.ピロリ菌 / 慢性炎症 / 活性酸素 / 病理学 / 8 hydroxy 2 / deoxyguanosne(8OHIG) / peroxiredoxin(PRDX) / 8-hydroxy-2'-deoxyguanosine (8OHdG) / peroxiredoxin (PRDX) / 8-hydroxy-2'-deoxyguanosine(80HdG) |
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| Research Abstract |
Although Helicobacter pylori(H. pylori)-i nfected chronic gastritis is described as accumulating reactive oxygen species(thinthe gastric epithelial cells and as relatingto the carcimgenesis, the further relationshiprenaiins to be conpletely elucidated. Inthis study, ve i nvesti gated the expression of RE relating substances in the gastric cancer and noncancerous gastric nuacosa, and conpared the expressi on i n gastritis, to difference young that patients, under 30 years of age, innot-young pat i ents, nmre than between the two groups. coexisting 40 years of H. age. pyrol 1-i of eat ed W found son
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