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The analysis for association of the polymorphisms of Stx prophage and host genome sequences in the production of Vero-toxin of enterohemorrhagic Echerichia coli

Research Project

Project/Area Number 22790424
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Bacteriology (including Mycology)
Research InstitutionToyama Institute of Health

Principal Investigator

KIMATA Keiko  富山県衛生研究所, 細菌部, 主任研究員 (50360805)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywords細菌 / 大腸菌 / 感染症
Research Abstract

This study was performed to analyze the polymorphic sequences of the downstream regions of stx2 or stx2c in enterohemorrhagic Escherichia coli (EHEC). By the phylogenic analysis, the polymorphic sequences of stx2c downstream regions were clustered in two groups without stx genotypes or serotype. The polymorphic sequences in stx2-downstream regions showed 3 clusters, one cluster with only O157 and the other clusters with main non-O157. The association was found between the polymorphic sequences in stx2-downstream regions and the host serotypes.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (5 results)

All 2013 2011

All Presentation (5 results)

  • [Presentation] 腸管出血性大腸菌(EHEC)のStx プロファ-ジ塩基配列多型の解析2013

    • Author(s)
      木全恵子
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉市 幕張メッセ
    • Related Report
      2012 Final Research Report
  • [Presentation] 腸管出血性大腸菌(EHEC)のStxプロファージ塩基配列多型の解析2013

    • Author(s)
      木全 恵子
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉市 幕張メッセ
    • Related Report
      2012 Annual Research Report
  • [Presentation] 可動性遺伝子に関連した複数の遺伝子型が検出されたO157 集団感染事例2011

    • Author(s)
      木全恵子
    • Organizer
      第15回腸管出血性大腸菌感染症研究会
    • Place of Presentation
      大阪市 浜北フォ-ラム
    • Year and Date
      2011-07-16
    • Related Report
      2012 Final Research Report
  • [Presentation] 可動性遺伝子に関連した複数の遺伝子型が検出されたO157集団感染事例2011

    • Author(s)
      木全恵子
    • Organizer
      第15回腸管出血性大腸菌感染症研究会
    • Place of Presentation
      大阪市浜北フォーラム
    • Year and Date
      2011-07-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 複数のDNA型を検出した腸管出血性大腸菌O157の集団感染事例について2011

    • Author(s)
      木全恵子
    • Organizer
      平成22年度地方衛生研究所全国協議会東海・北陸支部微生物部会
    • Place of Presentation
      地域交流プラザ アオッサ(福井県)
    • Year and Date
      2011-03-03
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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