Determination of detection and biological effect of formaldehyde exposure in food

Research Project

Project/Area Number	22790540
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Hygiene
Research Institution	Asahikawa Medical College
Principal Investigator	NAKAGI Yoshihiko 旭川医科大学, 医学部, 助教 (90322908)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000) Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000) Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	食品衛生 / ホルムアルデヒド / 食品 / 腸内細菌 / 大腸菌 / 生体影響
Research Abstract	Oral administration of formaldehyde via chow that were intended to be contained in the food caused reduction of number of E. coli in the gastrointestinal tract of mice and the disturbance the immune system of the gastrointestinal mucosa. Since formaldehyde-containing foods in the conventional extraction method of detection is likely to be underestimated and long term exposure to low level of formaldehyde to adversely affect the gastrointestinal tract immunity, the need for further safety assessment for the formaldehyde in foods has been shown.