| Project/Area Number |
22790563
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Public health/Health science
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | メタボリックシンドローム / 肥満 / 予防医学 / 特定健診・特定保健指導 / 尿中8-Hydroxydeoxyguanosine / 総死亡 / 動脈硬化 / 生活習慣病 / 心血管疾患 / アディポサイトカイン / 腹部肥満 |
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| Research Abstract |
We investigated the effects of the combination of metabolic syndrome and high-sensitivity C-reactive protein(hsCRP) level or urinary 8-hydroxydeoxyguanosine(OHdG) on cardiovascular disease and all-cause death in general Japanese population. In the cross sectional study, combination of MetS and hsCRP was a good indicator for prevalence of cardiovascular disease. In the prospective study, combination of MetS and hsCRP or 8-OHdG tended to be predictors for all-cause death but we could not find statistically significant relations. The combination of MetS and hsCRP or 8-OHdG may become a good predictor for cardiovascular disease and all-cause death and further follow-up of those participants may be needed to assess these relations.
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