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Prognosis and causes of death among patients with childhood-onset type 1 diabetes at the 45-year duration

Research Project

Project/Area Number 22790573
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Public health/Health science
Research InstitutionJikei University School of Medicine

Principal Investigator

MORIMOTO Aya  東京慈恵会医科大学, 医学部, 助教 (70385368)

Co-Investigator(Renkei-kenkyūsha) TAJIMA Naoko  東京慈恵会医科大学, 医学部, 名誉教授 (70112836)
NISHIMURA Rimei  東京慈恵会医科大学, 医学部, 准教授 (20343535)
SANO Hironari  東京慈恵会医科大学, 医学部, 講師 (20408404)
ONDA Yoshiko  東京慈恵会医科大学, 医学部, 大学院生
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords1 型糖尿病 / 疫学 / 予後 / 生存率 / 1型糖尿病 / 死因
Research Abstract

The study comprised 1,385 patients who were diagnosed as having type 1 diabetes before the age of 18 years during 1965 and 1979. The mortality risk of this cohort as of 2010 was 10.1-fold higher than that of the general population, and males had a 1.4-fold higher risk than did females. However, the mortality risk at the 30-year follow-up markedly improved from 19.0 in the 1965-69 diagnosis group to 6.9 in the 1975-79 diagnosis group. The causes of death will be analyzed after a discussion in the mortality classification committee.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (10 results)

All 2012 2011 2010

All Journal Article (1 results) Presentation (8 results) Book (1 results)

  • [Journal Article] Epidemiology of Childhood Diabetes Mellitus in Japan.2012

    • Author(s)
      Naoko Tajima, Aya Morimoto
    • Journal Title

      Pediatric Endocrinology Reviews Suppl. 1.

      Volume: 10 Pages: 44-50

    • Related Report
      2012 Final Research Report
  • [Presentation] Who Treats Patients with Childhood-Onset Adult Type 1 Diabetes in Japan - The Pediatrician or Internist? Results from the DERI Mortality Study2012

    • Author(s)
      Aya Morimoto, Yoshiko Onda, Rimei Nishimura, Hironari Sano, Kazunori Utsunomiya, Naoko Tajima
    • Organizer
      9th IDF-WPR Congress and 4th AASD Scientific Meeting.
    • Place of Presentation
      京都
    • Year and Date
      2012-11-26
    • Related Report
      2012 Final Research Report
  • [Presentation] DERI 研究班.小児期発症 1型糖尿病患者における失明と死因の関係:DERI Mortality Study2012

    • Author(s)
      森本彩、西村理明、佐野浩斎、田嶼尚子、宇都宮一典
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Year and Date
      2012-05-19
    • Related Report
      2012 Final Research Report
  • [Presentation] Causes of death after initiation of dialysis among patients with childhood-onset type 1 diabetes in Japan - DERI Mortality Study2011

    • Author(s)
      Aya Morimoto, Rimei Nishimura, Hironari Sano, Kazunori Utsunomiya, Naoko Tajima
    • Organizer
      47th Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      ポルトガル
    • Year and Date
      2011-09-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Causes of death after initiation of dialysis among patients with childhood-onset type 1 diabetes in Japan-DERI Mortality Study2011

    • Author(s)
      Aya Morimoto, et al
    • Organizer
      The 47th EASD Annual Meeting
    • Place of Presentation
      リスボン(ボルトガル)
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] DERI 研究班.小児期発症 1 型糖尿病患者における透析導入の有無と死因の関係- DERI Mortality Study -2011

    • Author(s)
      森本彩、田嶼尚子、西村理明、佐野浩斎、松平透、宇都宮一典
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Year and Date
      2011-05-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Long-term mortality and causes of death among patients with type 1 diabetes in Japan2010

    • Author(s)
      Aya Morimoto, Rimei Nishimura, Hironari Sano, Toru Matsudaira, Naoko Tajima, Kazunori Utsunomiya
    • Organizer
      46th Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      スウェーデン
    • Year and Date
      2010-09-22
    • Related Report
      2012 Final Research Report
  • [Presentation] Long-term mortality and causes of death among patients with type 1 diabetes in Japan2010

    • Author(s)
      Aya Morimoto, et al.
    • Organizer
      The 46th EASD Annual Meeting
    • Place of Presentation
      ストックホルム
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] DERI 研究班.小児期発症 1 型糖尿病患者における追跡開始後最長2010

    • Author(s)
      森本彩、西村理明、松平透、佐野浩斎、田嶼尚子、宇都宮一典
    • Organizer
      35 年次の予後調査-死因を含めて.第53回日本糖尿病学会年次学術集会
    • Year and Date
      2010-05-27
    • Related Report
      2012 Final Research Report
  • [Book] 糖尿病専門医研修ガイドブック改訂第5 版 第2章 糖尿病の疫学2012

    • Author(s)
      森本彩,西村理明,田嶼尚子
    • Publisher
      診断と治療社
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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