| Project/Area Number |
22790611
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | Tohoku University |
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Principal Investigator |
SEKIGUCHI Atsushi 東北大学, 東北メディカル・メガバンク機構, 講師 (50547289)
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| Co-Investigator(Renkei-kenkyūsha) |
KAWASHIMA Ryuta 東北大学, 加齢医学研究所, 教授 (90250828)
SUGIURA Motoaki 東北大学, 加齢医学研究所, 准教授 (60396546)
KOTOZAKI Yuka 東北大学, 加齢医学研究所, 研究員 (10569578)
FUKUDO Shin 東北大学, 医学系研究科, 教授 (80199249)
MORISHITA Joe 東北大学, 医学系研究科, 研究員 (00375031)
AIZAWA Emiko 独立行政法人国立精神・神経医療研究センター, 神経研究所・疾病研究第三部, 研究員 (00639049)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 脳・神経 / ストレス / 心身症 / 感情抑制 / 震災ストレス / 心身相関 |
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| Research Abstract |
We investigated neural bases underlying common psychological characteristics among psychosomatic diseases, such as stress vulnerability and somatization, by using neuroimaging methods. The results suggested that neural correlates of stress vulnerability is related to dysfunction of the dorsolateral prefrontal cortex and the ventral anterior cingulate cortex, and those of somatization is related to altered activation patterns in the anterior insula and the somatosensory area. The results support the effectiveness of psychological intervention to the patients with any types of psychosomatic diseases.
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