| Project/Area Number |
22790699
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Nagoya University |
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Principal Investigator |
ISHII Hideki 名古屋大学, 大学院・医学系研究科, 助教 (90456674)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 循環器 / 冠動脈 / 腎障害 / 血管内超音波 / 冠動脈形成術 / 動脈硬化 / 慢性腎疾患 / 心筋障害 |
|---|
| Research Abstract |
The present study was conducted to identify any relationship between estimated glomerular filtration rate(eGFR) and coronary plaque characteristics using integrated backscatter intravascular ultrasound(IB-IVUS) which can detect coronary plaque composition. eGFR significantly correlated with both parameters(r=-0. 68, p<0. 001 and r=0. 69, p<0. 001, respectively). In conclusion, lower eGFR levels are associated with higher lipid and lower fibrous contents, contributing to coronary plaque vulnerability.
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