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Analysis of roles and physiological functions of Intrinsic Cardiac Adrenergic Cell in rodent cardiac transplantation model.

Research Project

Project/Area Number 22790727
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Circulatory organs internal medicine
Research InstitutionKeio University

Principal Investigator

TAMURA Yuichi  慶應義塾大学, 医学部, 特任助教 (00468498)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords分子心臓病態学 / 組織幹細胞 / 心臓移植 / 神経提
Research Abstract

We identified the Intrinsic Cardiac Adrenergic Cell(ICA cell) are derived from neural crest by analyzing P0-Cre x Floxed-GFP transgenic mice. We found a driving factor for promoting the proliferation and differentiation into ICA cell. And we confirmed the contraction and heart rate of transplanted hearts were affected with the development of ICA cell.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (2 results)

All 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results)

  • [Journal Article] Neural crest-derived stem cells migrate and differentiate into cardiomyocytes after myocardial infarction2011

    • Author(s)
      Tamura Y, Matsumura K, Sano M, Tabata H, Kimura K, Ieda M, Arai T, Ohno Y, Kanazawa H, Yuasa S, Kaneda R, Makino S, Nakajima K, Okano H, Fukuda K
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 31(3) Pages: 582-9

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural crest-derived stem cells migrate and differentiate into cardiomyocytes after myocardial infarction.2011

    • Author(s)
      Yuichi Tamura
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 31 Pages: 582-589

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

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