Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Research Abstract |
Neuronal migration is essential for proper cortical layer formation, as migration defects result in neurological disorders. The locomotion mode of neuronal migration covers most of the migration route and thereby is the main contributor to cortical layer formation. However, analysis of the molecular mechanisms regulating this mode is difficult. In this study, we used an ex vivo chemical inhibitor screening, allowing us to directly analyze the locomotion mode of migration, and found several regulatory molecules regurating the locomotion mode.
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