Analysis on mechanism that translocates p27Kip1 into nuclei in neuronal progenitor cells in vivo
Project/Area Number |
22791001
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Pediatrics
|
Research Institution | Keio University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 神経発生 / 細胞周期 / プロモータ / 神経幹細胞 / 大脳皮質 |
Research Abstract |
p27Kip1, one of the cell cycle regulatory genes, play a critical role in differentiation of neuronal progenitor cells (NPCs). A purpose of this research was to elucidate the mechanism controlling nuclear accumulation of p27Kip1 proteins. We conducted immu
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Report
(4 results)
Research Products
(14 results)