| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
We have performed a comparative study about de novo melanomaand nevus-associated melanoma which obtained from each model mice using pathologicaland biological method. As a result, a characteristic alteration of gene expression in de novomelanoma was found. By further analysis using human melanoma tissues, we suggest thepossibility that this gene is associated with melanoma tumorigenesis in relation to E,which is involved in de novo melanoma tumorigenesis.
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