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Neuroimage and sleep in chronic pain patient(fibromyalgia)

Research Project

Project/Area Number 22791142
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionJuntendo University

Principal Investigator

USUI Chie  順天堂大学, 医学部, 准教授 (70453587)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords神経科学 / 脳・神経 / 臨床 / 線維筋痛症 / SPECT / 慢性疼痛 / 睡眠 / 脳機能画像
Research Abstract

Purpose : The aim of the present study was to determine the brain areas associated with fibromyalgia. Methods : A total of 10 women with fibromyalgia and 10 healthy women(without pain) matched for age were finally enrolled in the study. <18>^F-FDG-PET was performed in the fibromyalgia patients and controls. A voxel-by-voxel group analysis was performed using Statistic Parametric Mapping 5(SPM5). Results : We observed rCBF abnormalities, compared to control subjects, in fibromyalgia including hypometabolism in the middle temporal gyrus. Conclusions : The present study revealed brain regions with significant hypometabolism associated with the cognitive function.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (48 results)

All 2012 2011 2010

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (25 results) Book (8 results)

  • [Journal Article] The Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale : reliability and validity2012

    • Author(s)
      Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Ito K, Yamano Y, Nakamura H, Nakajima T, Nishioka K
    • Journal Title

      Mod Rheumatol

      Volume: 22 Pages: 40-44

    • NAID

      10030206754

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Difference in early prediction of antipsychotic non-response between risperidone and olanzapine in the treatment of acute-phase schizophrenia2011

    • Author(s)
      Hatta K, Otachi T, Sudo Y, Hayakawa T, Ashizawa Y, Takebayashi H, Hayashi N, Hamakawa H, Ito S, Nakase R, Usui C, Nakamura H, Hirata T, Sawa Y
    • Journal Title

      Schizophr Res

      Volume: 128(1-3) Pages: 127-135

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Improvements in both psychosis and motor signs in Parkinson's disease, and changes in regional cerebral blood flow after electroconvulsive therapy2011

    • Author(s)
      Usui C, Hatta K, Doi N, Kubo S, Kamigaichi R, Nakanishi A, Nakamura H, Hattori N, Arai H
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 35(7) Pages: 1704-8

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Vitamin K deficiency due to prolongation of antibiotic treatment and decrease in food intake in a catatonia patient2011

    • Author(s)
      Nomoto H, Hatta K, Usui C, Ito M, Kita Y, Arai H
    • Journal Title

      Psychosomatics

      Volume: 52(5) Pages: 486-7

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Difference in early prediction of antipsychotic non-response between rispe ridone and olanzapine in the treatment of acute-phase schizophrenia2011

    • Author(s)
      Hatta K, et al
    • Journal Title

      Schizophr Res

      Volume: 128 Pages: 127-135

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Improvements in both psychosis and motor signs in Parkinson's disease, and changes in regional cerebral blood flow after electroconvulsive therapy2011

    • Author(s)
      Usui.C
    • Journal Title

      Prog.Neuropsychopharmacol.Biol.Psychiatry

      Volume: Vol.35 Issue: 7 Pages: 1704-1708

    • DOI

      10.1016/j.pnpbp.2011.05.003

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Vitamin K deficiency due to prolongation of antibiotic treatment and decrease in food intake in a catatonia patien t2011

    • Author(s)
      Nomoto H, et al
    • Journal Title

      Psychosomatics

      Volume: 52 Pages: 486-487

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Open wards versus locked wards of general hospitals in the treatment of psychiatric patients with medical comorbidities : a cross-sectional study in Tokyo2010

    • Author(s)
      Hatta K, Usui C, Nakamura H, Kurosawa H, Arai H
    • Journal Title

      Psychiatry Clin Neurosci

      Volume: 64(1 Pages: 52-6

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin2010

    • Author(s)
      Usui C, Hatta K, Doi N, Nakanishi A, Nakamura H, Nishioka K, Arai H.
    • Journal Title

      Arthritis Res Ther

      Volume: 12(2)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A prospective naturalistic multicentre study of intravenous medications in behavioural emergencies : haloperidol versus flunitrazepam2010

    • Author(s)
      Hatta K, Nakamura M, Yoshida K, Hamakawa H, Wakejima T, Nishimura T, Furuta K, Kawabata T, Hirata T, Usui C, Nakamura H, Sawa Y
    • Journal Title

      Psychiatry Res

      Volume: 178(1) Pages: 182-5

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Utility and sufficiency of psychiatric inpatient units in general hospitals : a cross-sectional study in Tokyo2010

    • Author(s)
      Hatta K, Nakamura H, Usui C, Kurosawa H
    • Journal Title

      Psychiatry Clin Neurosci

      Volume: 64(6) Pages: 642-644

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin.2010

    • Author(s)
      Usui C, Hatta K, Doi N, Nakanishi A, Nakamura H, Nishioka K, Arai H.
    • Journal Title

      Arthritis Res Ther

      Volume: 7;12(2)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Open wards versus locked wards of general hospitals in the treatment of psychiatric patients with medical comorbidities : a cross-sectional study in Tokyo.2010

    • Author(s)
      Hatta K, Usui C, Nakamura H, Kurosawa H, Arai H
    • Journal Title

      Psychiatry Clin Neurosci.

      Volume: 64(1) Pages: 52-56

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A prospective naturalistic multicentre study of intravenous medications in behavioural emergencies : haloperidol versus flunitrazepam.2010

    • Author(s)
      Hatta K, Nakamura M, Yoshida K, Hamakawa H, Wakejima T, Nishimura T, Furuta K, Kawabata T, Hirata T, Usui C, Nakamura H, Sawa Y
    • Journal Title

      Psychiatry Res

      Volume: 178(1) Pages: 182-185

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Utility and sufficiency of psychiatric inpatient units in general hospitals : a cross-sectional study in Tokyo.2010

    • Author(s)
      Hatta K, Usui C, Nakamura H, Kurosawa H
    • Journal Title

      Psychiatry Clin Neurosci.

      Volume: 64(6) Pages: 642-644

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 米国リウマチ学会診断予備基準2010の本邦例での検証「線維筋痛症診療ガイドライン」改訂コンセンサスカンファレンス2011

    • Author(s)
      臼井千恵
    • Year and Date
      2011-04-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 不眠・抑うつ状態に対する薬物療法「線維筋痛症診療ガイドライン」改訂コンセンサスカンファレンス2011

    • Author(s)
      臼井千恵
    • Year and Date
      2011-04-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 認知行動療法、精神療法、心理療法など「線維筋痛症診療ガイドライン」改訂コンセンサスカンファレンス2011

    • Author(s)
      臼井千恵
    • Year and Date
      2011-04-27
    • Related Report
      2011 Final Research Report
  • [Presentation] ACR予備基準2010の本邦での検証2011

    • Author(s)
      臼井千恵、荒谷聡子、八木下尚子、西岡健弥、伊藤健司、山野嘉久、中島利博、西岡久寿樹
    • Organizer
      第3回線維筋痛症学会
    • Related Report
      2011 Final Research Report
  • [Presentation] 線維筋痛症の脳機能画像-病態解明・診断・治療にむけて-2011

    • Author(s)
      臼井千恵
    • Organizer
      第3回線維筋痛症学会
    • Related Report
      2011 Final Research Report
  • [Presentation] 線維筋痛症のSPECT所見およびガバペンチンの有効性の予測について2011

    • Author(s)
      臼井千恵、八田耕太郎、新井平伊
    • Organizer
      第107回日本精神神経医学会総会
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] ACR予備診断基準2010の本邦での検証2011

    • Author(s)
      臼井千恵、八田耕太郎
    • Organizer
      第24回総合病院精神医学会総会
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 精神病症状を伴うパーキンソン病におけるECTの有効性と脳血流の変化2011

    • Author(s)
      臼井千恵、八田耕太郎、土井永史、新井平伊
    • Organizer
      第24回総合病院精神医学会総会
    • Related Report
      2011 Final Research Report
  • [Presentation] ECTの新しい適応2011

    • Author(s)
      臼井千恵
    • Organizer
      第24回総合病院精神医学会総会
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin2011

    • Author(s)
      Usui C, Hatta K, Doi N, Nakanishi A, Nakamura H, Nishioka K
    • Organizer
      1^<st> BIO-RHEUMATOLOGY INTERNATIONAL CONGRESS(BRIC)
    • Place of Presentation
      Tokyo JAPAN
    • Related Report
      2011 Final Research Report
  • [Presentation] ACR予備基準2010の本邦での検証2011

    • Author(s)
      臼井千恵、荒谷聡子, 他
    • Organizer
      第3回線維筋痛症学会
    • Place of Presentation
      横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] 線維筋痛症の脳機能画像~病態解明・診断・治療にむけて~2011

    • Author(s)
      臼井千恵
    • Organizer
      第3回線維筋痛症学会
    • Place of Presentation
      横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] 精神病症状を伴うパーキンソン病におけるECTの有効性と脳血流の変化2011

    • Author(s)
      臼井千恵、八田耕太郎, 他
    • Organizer
      第24回総合病院精神医学会総会
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin2011

    • Author(s)
      Usui C, Hatta K, Doi N, Nakanishi A, Nakamura H, Nishioka K
    • Organizer
      1^<st> BIO-RHEUMATOLOGY INTERNATIONAL CONGRESS (BRIC)
    • Place of Presentation
      Tokyo
    • Related Report
      2011 Annual Research Report
  • [Presentation] 線維筋痛症のSPECT所見およびガバペンチンの有効性の予測について2010

    • Author(s)
      臼井千恵
    • Organizer
      第13回脳核医学研究会
    • Year and Date
      2010-09-04
    • Related Report
      2011 Final Research Report
  • [Presentation] 線維筋痛症のSPECT所見およびガバペンチンの有効性の予測について2010

    • Author(s)
      臼井千恵
    • Organizer
      第13回 脳核医学研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 線維筋痛症のSPECT所見およびガバペンチンの有効性の予測について2010

    • Author(s)
      臼井千恵、荒谷聡子、八木下尚子、西岡健弥、伊藤健司、山野嘉久、中島利博、西岡久寿樹
    • Organizer
      第2回線維筋痛症学会
    • Related Report
      2011 Final Research Report
  • [Presentation] カレントトピックス2010ACR予備診断基準について-精神科医の立場から-2010

    • Author(s)
      臼井千恵、西岡久寿樹
    • Organizer
      第2回線維筋痛症学会
    • Related Report
      2011 Final Research Report
  • [Presentation] 線維筋痛症のSPECT所見およびガバペンチンの有効性の予測について2010

    • Author(s)
      臼井千恵
    • Organizer
      第23回総合病院精神医学会総会
    • Related Report
      2011 Final Research Report
  • [Presentation] ECTの適応の拡大2010

    • Author(s)
      臼井千恵
    • Organizer
      第22回日本総合病院精神医学会総会ECT講習会
    • Related Report
      2011 Final Research Report
  • [Presentation] 改訂された線維筋痛症の新しい診断基準(ACR2010)の本邦患者の評価2010

    • Author(s)
      岡寛、松本美富士、淺沼ゆう、伊藤健司、中島利博、荒谷聡子、山野嘉久、臼井千恵、西岡健弥、友利新、佐野みほろ、長田賢一、藤田宗久、西岡久寿樹
    • Organizer
      第25回日本臨床リウマチ学会
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 線維筋痛症のSPECT所見およびガバペンチンの有効性の予測について2010

    • Author(s)
      臼井千恵、荒谷聡子、八木下尚子、西岡健弥、伊藤健司、山野嘉久、中島利博、西岡久寿樹
    • Organizer
      第2回 線維筋痛症学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] カレントトピックス 2010ACR予備診断基準について~精神科医の立場から~2010

    • Author(s)
      臼井千恵、西岡久寿樹
    • Organizer
      第2回 線維筋痛症学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 線維筋痛症のSPECT所見およびガバペンチンの有効性の予測について2010

    • Author(s)
      臼井千恵
    • Organizer
      第23回日本総合病院精神医学会総会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] ECTの適応の拡大2010

    • Author(s)
      臼井千恵
    • Organizer
      第23回日本総合病院精神医学会総会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Book] 慢性疲労症候群と線維筋痛症.睡眠医学アトラス検査と臨床2012

    • Author(s)
      臼井千恵
    • Publisher
      真興交易(株)図書出版
    • Related Report
      2011 Final Research Report
  • [Book] 睡眠医学アトラス検査と臨床(野沢胤美編)2012

    • Author(s)
      野沢胤美編, 臼井千恵(分担)
    • Total Pages
      286
    • Publisher
      真興交易(株)図書出版
    • Related Report
      2011 Annual Research Report
  • [Book] 不眠・抑うつ状態に対する薬物療法、認知行動療法、精神療法、心理療法など.線維筋痛症診療ガイドライン2011

    • Author(s)
      臼井千恵
    • Publisher
      日本醫事新報出版社
    • Related Report
      2011 Final Research Report
  • [Book] 向精神薬・身体疾患治療薬の相互作用に関する指針2011

    • Author(s)
      日本総合病院精神医学会, 治療戦略検討委員会
    • Publisher
      星和書店
    • Related Report
      2011 Final Research Report
  • [Book] 線維筋痛症診療ガイドライン2011(日本線維筋痛症学会編)2011

    • Author(s)
      日本線維筋痛症学会編, 臼井千恵(分担)
    • Total Pages
      207
    • Publisher
      日本醫事新報出版社
    • Related Report
      2011 Annual Research Report
  • [Book] 向精神薬・身体疾患治療薬の相互作用に関する指針日本総合病院精神医学会(治療戦略検討委員会編)2011

    • Author(s)
      治療戦略検討委員会編, 臼井千恵(分担)
    • Total Pages
      277
    • Publisher
      星和書店
    • Related Report
      2011 Annual Research Report
  • [Book] 痛みに関連した疾患(線維筋痛症).青春期精神医学2010

    • Author(s)
      臼井千恵
    • Publisher
      診断と治療社
    • Related Report
      2011 Final Research Report
  • [Book] 痛みに関連した疾患(線維筋痛症),青春期精神医学2010

    • Author(s)
      臼井千恵
    • Publisher
      診断と治療社
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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