| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
We examined the pharmacological mechanisms of exercise on depression. This study included 12 patients with depression in our university hospital and 36 healthy controls. Ham-D and SDS score were significantly decreased after 8-week exercise in the patients with depression. Exercise significantly increased NOx (P<0.05) and MHPG (P<0.01), but not BDNF, HVA, blood biochemical exam, blood pressure, body mass index and west in depression. We assessed MRI and SPECT only one patient with depression. The cerebral blood flow with the patient was improved after the exercise. There were no associations between improvement of depression and the levels of BDNF, NOx, MHPG, HVA in before exercise. Exercise significantly decreased HVA (P<0.05), but not BDNF, NOx, MHPG, blood biochemical exam, blood pressure, body mass index and west in control. We cannot assess MRI and SPECT on healthy control.
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