Lithium level in drinking water and mental health in adolescents

• Project/Area Number: 22791158
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Psychiatric science
• Research Institution: 公益財団法人東京都医学総合研究所 (2012); Tokyo Metropolitan Organization for Medical Research (2010-2011)
• Principal Investigator: NISHIDA Atsushi 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主任研究員 (20510598)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: リチウム / 水道水 / 思春期精神保健 / 自殺関連問題 / 疫学 / 学校精神保健 / 思春期 / 精神保健 / 衝動性 / 水

Research Abstract

This study showed examined the association between low level of lithium in drinking water and mental health problems including suicidal problems in adolescents. The results indicated that there significant association between low level of lithium in drinking water and reduced impulsivity and depression among general adolescents. The result of this study added further evidence on the anti-suicidal mechanism of clinical use of lithium in which lithium directly affects on impulsivity rather than depressed mood.

Research Products

• [Journal Article] A greater number of somatic pain sites is associated with poor mental health in adolescents: a cross-sectional study. (2013)
  • Author(s): Ando S, Yamasaki S, Shimodera S, Sasaki T, Oshima N, Furukawa TA, Astukai N, Kasai K, Mino Y, Inoue S, Okazaki Y, Nishida A
  • Journal Title: BMC Psychiatry Volume: 17;13 Issue: 1 Pages: 30-30
  • DOI: 10.1186/1471-244x-13-30
  • Peer Reviewed
• [Journal Article] Help seeking behaviors among Japanese school students who self-harm; results from a self-report survey with 18,104 adolescents (2012)
  • Author(s): Watanabe N
  • Journal Title: Neuropsychiatr Dis Treat Volume: 8 Pages: 561-569
  • DOI: 10.2147/ndt.s37543
  • Peer Reviewed
• [Journal Article] Irregular bedtime and nocturnal cellular phone usage as risk factors for being involved in bullying; a cross-sectional survey of Japanese adolescents (2012)
  • Author(s): Tochigi M
  • Journal Title: PLoS ONE Volume: 7 Issue: 9 Pages: 1-6
  • DOI: 10.1371/journal.pone.0045736
  • Peer Reviewed
• [Journal Article] Deliberate self-harm in adolescents aged 12 -18; a cross-sectional survey of 18,104 students (2012)
  • Author(s): Watanabe N & Nishida A
  • Journal Title: Suicide Life Threat Behav Volume: 42 Issue: 5 Pages: 550-560
  • DOI: 10.1111/j.1943-278x.2012.00111.x
  • Peer Reviewed
• [Journal Article] The suicidal feelings, self-injury, and mobile phone use after lights out in adolescents (2012)
  • Author(s): Oshima N, Nishida A, Shimodera S, Tochigi M, Ando S, Yamasaki S, Okazaki Y, Sasaki T
  • Journal Title: J Pediatr Psychol Volume: 37 Pages: 1023-30
  • Peer Reviewed
• [Journal Article] Public speaking fears and their correlates among 18,104 Japanese adolescents (2012)
  • Author(s): Furukawa TA, Watanabe N, Nishida A, Okazaki Y, Shimodera S
  • Journal Title: Asia-Pacific Psychiatry Volume: 11 Issue: 1 Pages: 99-104
  • DOI: 10.1111/j.1758-5872.2012.00184.x
  • Peer Reviewed
• [Journal Article] but also body mass index is relebant to suicidal ideation and self-harm be (2012)
  • Author(s): hita K, Shimodera S, Nishida A, et
  • Journal Title: J Nerv Ment Dis Volume: 200 Pages: 305-309
  • Peer Reviewed
• [Journal Article] agoraphobia is associated with the symptoms and location of a patient's fir (2012)
  • Author(s): ra N, Nishimura Y, Nishida A, et al
  • Journal Title: Biopsychosoc Med Volume: 6 Pages: 12-12
  • Peer Reviewed
• [Journal Article] Pshchotic-like experiences are associated with violent behavior in adoles cents. (2011)
  • Author(s): Kinoshita Y, Shimodera S, Nishida A, et al
  • Journal Title: Schizophrenia Research Volume: 126 Pages: 245-251
  • Peer Reviewed
• [Journal Article] Family psychoeducation for major depression randomized controlled trial. (2011)
  • Author(s): Shimazu K, Shimodera S, Mino Y, Nishida A, et al
  • Journal Title: British Journal of Psychiatry Volume: 198 Pages: 385-390
  • Peer Reviewed
• [Journal Article] Psychotic-like experiences(PLEs) and mental health status in twin and singlestone Japanese high school students. (2010)
  • Author(s): Oshima N, Nishida A, et al
  • Journal Title: Early Intervention in Psychiatry Volume: 4 Pages: 206-213
  • Peer Reviewed
• [Presentation] (シンポジウム).社会階層と思春期の精神保健 (2012)
  • Author(s): 西田淳志
  • Organizer: 第16回日本精神保健・予防学会
  • Place of Presentation: 東京
  • Year and Date: 2012-12-16
• [Presentation] (シンポジウム).これからの回復支援 (2012)
  • Author(s): 西田淳志
  • Organizer: 第20回日本精神障害者リハビリテーション学会
  • Place of Presentation: 神奈川
  • Year and Date: 2012-11-17
• [Presentation] (シンポジウム).不安障害の疫学:コホート研究の知見を踏まえて (2012)
  • Author(s): 西田淳志
  • Organizer: 第4回日本不安障害学会学術大会
  • Place of Presentation: 東京
  • Year and Date: 2012-02-04
• [Presentation] 思春期における身体的疼痛の数と精神的不健康の関係 (2012)
  • Author(s): 安藤俊太郎、山崎修道、下寺信次、佐々木司、大島紀人、飛鳥井望、笠井清登、井上新平、岡崎祐士、西田淳志
  • Organizer: 第4回日本不安障害学会学術大会
  • Place of Presentation: 東京
  • Year and Date: 2012-02-04
• [Presentation] 生物学的精神医学研究におけるコホート研究の役割 (2011)
  • Author(s): 西田淳志
  • Organizer: 第33回日本生物学的精神医学会
  • Place of Presentation: 東京(招待講演)
  • Year and Date: 2011-05-22
• [Presentation] Risk of suicidal problems : A comparison of help-seeking and non-help-seeking groups of adolescents with psychotic-like experiences. (2010)
  • Author(s): Nishida A, et al
  • Organizer: International Early Psychosis Association(IEPA)Conference
  • Place of Presentation: Amsterdam International Conference Centre
  • Year and Date: 2010-11-30
• [Remarks]
  • URL: http://prit.igakuken.or.jp/Ja/Archives/arch10.html#PKokoro