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Analysis of brain connectivity using functional MRI and diffusion-weighted imaging

Research Project

Project/Area Number 22791178
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionThe University of Tokyo

Principal Investigator

TAKAO Hidemasa  東京大学, 医学部附属病院, 助教 (10444093)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords核磁気共鳴画像(MRI) / 拡散強調画像 / 安静時脳機能画像 / コネクティビティ
Research Abstract

For reliable analysis of structural and functional connectivity of the human brain using diffusion-weighted imaging and resting state functional MRI, we first analyzed inter-scanner and intra-scanner variability, longitudinal stability, scanner upgrade effects, etc. and showed their effects on brain connectivity analysis. Based on these results, we examined methods of analysis of brain connectivity using diffusion-weighted imaging and resting state functional MRI, applied them to data obtained on normal subjects, and confirmed the validity of the methods.

Report

(3 results)
  • 2012 Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (17 results)

All 2012 2011 2010

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (8 results)

  • [Journal Article] Effect of scanner in longitudinal diffusion tensor imaging studies.2012

    • Author(s)
      Takao H, Hayashi N, Kabasawa H, Ohtomo K.
    • Journal Title

      Hum Brain Mapp.

      Volume: 33(2) Issue: 2 Pages: 466-77

    • DOI

      10.1002/hbm.21225

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of head size on diffusion tensor imaging.2011

    • Author(s)
      Takao H, Hayashi N, Inano S, Ohtomo K.
    • Journal Title

      Neuroimage.

      Volume: 57(3) Issue: 3 Pages: 958-67

    • DOI

      10.1016/j.neuroimage.2011.05.019

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of scanner in longitudinal studies of brain volume changes.2011

    • Author(s)
      Takao H, Hayashi N, Ohtomo K.
    • Journal Title

      J Magn Reson Imaging.

      Volume: 34(2) Issue: 2 Pages: 438-44

    • DOI

      10.1002/jmri.22636

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of scanner in asymmetry studies using diffusion tensor imaging.2011

    • Author(s)
      Takao H, Hayashi N, Ohtomo K.
    • Journal Title

      Neuroimage.

      Volume: 15;54(2) Issue: 2 Pages: 1053-62

    • DOI

      10.1016/j.neuroimage.2010.09.023

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of scanner in asymmetry studies using diffusion tensor imaging2011

    • Author(s)
      高尾英正
    • Journal Title

      NeuroImage

      Volume: 54 Pages: 1053-1062

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Computational analysis of cerebral cortex.2010

    • Author(s)
      Takao H, Abe O, Ohtomo K.
    • Journal Title

      Neuroradiology.

      Volume: 52(8) Issue: 8 Pages: 691-8

    • DOI

      10.1007/s00234-010-0715-4

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of gradient non-linearity correction and intensity non-uniformity correction in longitudinal studies using structural image evaluation using normalization of atrophy (SIENA).2010

    • Author(s)
      Takao H, Abe O, Hayashi N, Kabasawa H, Ohtomo K
    • Journal Title

      J Magn Reson Imaging

      Volume: 32(2) Issue: 2 Pages: 489-92

    • DOI

      10.1002/jmri.22237

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Computational analysis of cerebral cortex2010

    • Author(s)
      高尾英正
    • Journal Title

      Neuroradiology

      Volume: 52 Pages: 691-698

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of gradient non-linearity correction and intensity non-uniformity correction in longitudinal studies using SIENA2010

    • Author(s)
      高尾英正
    • Journal Title

      Journal of Magnetic Resonance Imaging

      Volume: 32 Pages: 489-492

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Sex dimorphism in white matter integrity.2012

    • Author(s)
      Hidemasa Takao, Naoto Hayashi, Kuni Ohtomo.
    • Organizer
      European Congress of Radiology (ECR 2012)
    • Place of Presentation
      Vienna (Austria)
    • Related Report
      2012 Final Research Report
  • [Presentation] Sex dimorphism in white matter integrity2012

    • Author(s)
      高尾英正
    • Organizer
      European Congress of Radiology (ECR 2012)
    • Place of Presentation
      ウィーン(オーストリア)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳とテンソル画像2011

    • Author(s)
      高尾英正、大友邦
    • Organizer
      日本医学放射線学会秋季臨床大会
    • Place of Presentation
      海峡メッセ下関(山口県)
    • Related Report
      2012 Final Research Report
  • [Presentation] 頭の大きさは拡散テンソル画像に影響を与える2011

    • Author(s)
      高尾英正、林直人、大友邦
    • Organizer
      日本磁気共鳴医学会大会.
    • Place of Presentation
      リーガロイヤルホテル小倉(福岡県)
    • Related Report
      2012 Final Research Report
  • [Presentation] 頭の大きさは拡散テンソル画像に影響を与える2011

    • Author(s)
      高尾英正
    • Organizer
      日本磁気共鳴医学会大会
    • Place of Presentation
      リーガロイヤルホテル小倉(福岡県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳とテンソル画像2011

    • Author(s)
      高尾英正
    • Organizer
      日本医学放射線学会秋季臨床大会
    • Place of Presentation
      海峡メッセ下関(山口県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳拡散テンソル画像におけるスキャナの影響2010

    • Author(s)
      高尾英正
    • Organizer
      日本磁気共鳴医学会大会
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Year and Date
      2010-09-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脳拡散テンソル画像におけるス キャナの影響2010

    • Author(s)
      高尾英正、林直人、阿部修、椛沢宏之、 大友邦
    • Organizer
      日本磁気共鳴医学会大会
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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