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Development of novel brachytherapy technique for various tumor sited that had never been treated

Research Project

Project/Area Number 22791194
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionOsaka University

Principal Investigator

TAKAHASHI Yutaka  大阪大学, 大学院・医学系研究科, 特任助教(常勤) (40353461)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2010: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords小線源治療 / 腔内モールド照射 / スキルス胃がん
Research Abstract

The purpose of this study was to develop the novel brachytherapy technique for various tumors that had never been treated including highly malignant schirrhous stomach carcinoma. First, novel applicator was designed so that the applicator can be swelled with great flexibility along the stomach wall. The dose measurement with this applicator was performed using film or BangGel. We found that film measurement was not suitable due to the response heterogeneity in the film. On the other hand, 3D gel dosimetry was found to be suitable owing to high spatial resolution and the dose around the stomach was rapidly fallen off. Further simulation study to examine the appropriate source position or radionuclide is required for appropriate treatment.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (4 results)

All 2012 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results)

  • [Journal Article] Homogeneity of Gafchromic EBT2 film among different lot numbers2012

    • Author(s)
      Mizuno H, Takahashi Y, Tanaka A et al
    • Journal Title

      J. Appl. Clin. Med. Phys.

      Volume: 13,(In press) Pages: 4-4

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Homogeneity of Gafchromic EBT2 film among different lot numbers2012

    • Author(s)
      Mizuno H, Takahashi Y, et al
    • Journal Title

      Journal of Applied Clinical Medical Physics

      Volume: (In press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Semi-independent plan verification m ethod for high-dose-rate intracavitary brachytherapy using benchmark plan2011

    • Author(s)
      Takahashi Y, Koizumi M, Sumida I et a l
    • Organizer
      Amer ican Association of Physicist in Medicine 53^<rd> annual meeting
    • Place of Presentation
      Vancouver
    • Year and Date
      2011-07-31
    • Related Report
      2011 Final Research Report
  • [Presentation] Semi-independent plan verification method for high-dose-rate intracavitary brachytherapy using benchmark plan2011

    • Author(s)
      Yutaka Takahashi, et al
    • Organizer
      American Association of Physicist in Medicine 53^<rd> annual meeting
    • Place of Presentation
      Vancouver(カナダ)(招待講演)
    • Year and Date
      2011-07-28
    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

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