Development of respiratory functional imaging by using low-dose CT

• Project/Area Number: 22791197
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: Kobe University
• Principal Investigator: KOYAMA Hisanobu 神戸大学, 医学部附属病院, 講師 (30546487)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: エックス線 / CT / コンピュータ断層撮影 / X線被爆 / 機能画像診断 / 呼吸器 / X線被曝 / 機能画像

Research Abstract

The purpose of this study was to determine the capabilities of low-dose CT at the assessment of respiratory functional imaging. In this study, radiation exposure decreased to 25% of standard dose CT at the quantitative assessment of lung parenchyma by using automatic exposure control technique, and to 17% at the quantitative assessment of bronchus by using iterative noise reduction technique in pulmonary emphysema.

Research Products

• [Journal Article] Three-dimensional airway lumen volumetry: comparison with bronchial wall area and parenchymal densitometry in assessment of airway obstruction in pulmonary emphysema (2012)
  • Author(s): Koyama H, Ohno Y, Nishio M, Takenaka D, Yoshikawa T, Matsumoto S, Nishimura Y, Sugimura K
  • Journal Title: Br J Radiol Volume: 85(1020) Issue: 1020 Pages: 1525-32
  • DOI: 10.1259/bjr/22602417
  • Peer Reviewed
• [Journal Article] Reduced-dose chest CT with 3D automatic exposure control vs. standard chest CT : Quantitative assessment of emphysematous changes in smokers' lung parenchyma (2011)
  • Author(s): Koyama H, Ohno Y, Yamazaki Y, Matsumoto K, Onishi Y, Takenaka D, Yoshikawa T, Nishio M, Matsumoto S, Murase K, Nishimura Y, Sugimura K
  • Journal Title: Eur J Radiol Volume: (in press) Issue: 6 Pages: 1330-4
  • DOI: 10.1016/j.ejrad.2011.03.037
  • Peer Reviewed
• [Journal Article] Reduced-dose Chest CT with 3D Automatic Exposure Control vs.Stand ard Chest CT : Quantitative Assessment of Emphysematous Changes in Smokers' Lung Parenchyma
  • Author(s): Koyama H, Ohno Y, Yamazaki Y, et al(他9名,1番目)
  • Journal Title: European Journal of Radiology Volume: (In Press)(掲載確定)
  • Peer Reviewed
• [Presentation] 肺気腫患者の気管支定量評価における低線量CTの有用性の検討 (2013)
  • Author(s): 神山 久信,他
  • Organizer: 第72回日本医学放射線学会
  • Place of Presentation: 横浜
• [Presentation] The utility of adaptive iterative dose reduction using three dimensional processing (AIDR 3D) for quantitative bronchial assessment on low-dose thin-section MDCT in patients with pulmonary emphysema in comparison with filter back projection (2013)
  • Author(s): Hisanobu Koyama, et al
  • Organizer: 欧州放射線学会(ECR)2013
  • Place of Presentation: オーストリア、ウィーン
• [Presentation] The utility of adaptive iterative dose reduction using three dimensional processing (AIDR 3D) for quantitative bronchial assessment on low-dose thin-section MDCT in patients with pulmonary emphysema in comparison with filter back projection (2013)
  • Author(s): Hisanobu Koyama
  • Organizer: ECR
  • Place of Presentation: オーストリア （ウィーン）
• [Presentation] 肺気腫患者の気管支定量評価における低線量CTの有用性の検討 (2013)
  • Author(s): 神山 久信
  • Organizer: 日本医学放射線学会
  • Place of Presentation: 横浜
• [Presentation] Adaptive Iterative Dose Reduction using Three Dimensional Processing (AIDR 3D) vs. Filter Back Projection: Utility for Quantitative Bronchial Assessment on Low-doseThin-Section MDCT in Patients with Pulmonary Emphysema (2012)
  • Author(s): Hisanobu Koyama, et al
  • Organizer: 北米放射線学会(RSNA)2012
  • Place of Presentation: アメリカ、シカゴ
• [Presentation] 3D Airway Lumen Volumetry: Comparison to bronchial wall area and parenchymal densitometry in assessment of airway obstruction (2012)
  • Author(s): 神山 久信,他
  • Organizer: 第71回日本医学放射線学会総会・学術集会
  • Place of Presentation: 横浜
• [Presentation] Adaptive Iterative Dose Reduction using Three Dimensional Processing (AIDR 3D) vs. Filter Back Projection: Utility for Quantitative Bronchial Assessment on Low-doseThin-Section MDCT in Patients with Pulmonary Emphysema (2012)
  • Author(s): Hisanobu Koyama
  • Organizer: RSNA
  • Place of Presentation: アメリカ （シカゴ）
• [Presentation] Quantitative Bronchial Luminal Volumetric Assessment of Airflow Limitation on Thin-Section MDCT in Pulmonary Emphysema Patients (2011)
  • Author(s): Hisanobu Koyama, et al
  • Organizer: The 2nd Asian Congress of Thoracic Radiology
  • Place of Presentation: 京都