Establishment of the optimal dose fractionation of hypofractionated radiotherapy to head and neck cancer

Research Project

Project/Area Number	22791220
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Radiation science
Research Institution	International University of Health and Welfare
Principal Investigator	KAWASE Takatsugu 国際医療福祉大学, 保健医療学部, 准教授 (80306795)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000) Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords	頭頸部癌 / 少分割照射
Research Abstract	The aim of this study was to establish the optimal dose fractionation of hypofractionated radiotherapy for head and neck cancer. We analyzed converted dose-volume histograms with the linear-quadratic model derived from such histograms with usual 2Gy-fractional dose prescriptions. A target volume and organs at risk were delineated to analyze the difference among the histograms generated with respective alpha-beta ratios.