Molecular biological research on the sensitivity for the treatment of GBM focused on the carcinogenic process
| Project/Area Number |
22791224
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Tokyo Women's Medical University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 放射線腫瘍学 / 膠芽腫 / 放射線治療 / 発がん過程 / 分子生物学 / テモゾロマイド |
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| Research Abstract |
We focused on the difference of genetic background on the carcinogenic of GBM. First, in order to make it clear the each sensitivity of the chemoradotherapy, we divided into two groups of secondary and primary. Then we used a variety of cultured cell lines, including each group, and evaluated the sensitivity to radiotherapy, and tried to confirm the differences in radiation sensitivity between the two groups. Finally we tried to determine whether the hawk of apoptosis has been attributed to differences in sensitivity.
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Report
(3 results)
Research Products
(3 results)
