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Standardization of patient dosimetry and investigation of the efficacy of radioprotective agent during neuroendovascular procedure

Research Project

Project/Area Number 22791231
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research Institution公益財団法人冲中記念成人病研究所 (2012)
Okinaka Memorial Institute for Medical Research (2010-2011)

Principal Investigator

HAYAKAWA Mikito  公益財団法人冲中記念成人病研究所, 研究員 (80450229)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords蛍光ガラス線量計 / 皮膚透過線量 / インターベンショナル・ラジオロジー / 医療被ばく / 脳血管内治療 / インターベンショナルラジオロジー / 放射線 / 脳神経疾患
Research Abstract

We established a direct dosimetry method of patients’ entrance skin doses during neuroendovascular procedure using multiple radiophotoluminescence glass dosimeters. We applied this dosimetry system in clinical neuroendovascular settings, and clarified the frequency of maximum entrance skin dose (ESD) over 3 Gy, the prevalence of temporary epilation as a radiation-induced skin injury, and the difference of radiation-dose distributions between single-plane and bi-plane angiography equipments. In addition, we clarified that total fluoroscopic time and dose-area products were clearly related to maximum ESD and we could estimate the ESD in real-time during neuroendovascular procedure. These results could be the fundamental data to reduce radiation exposure during neuroendovascular procedure and to apply the radioprotective agent in a clinical setting in the near future.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (16 results)

All 2012 2011 2010

All Journal Article (3 results) (of which Peer Reviewed: 1 results) Presentation (13 results)

  • [Journal Article] Precise mapping system of entrance skin dose during endovascular embolization for cerebral aneurysm2011

    • Author(s)
      Moritake T, Hayakawa M, Matsumaru Y, Takigawa T, Koguchi Y, Miyamoto Y, Mizuno Y, Chida K, Akahane K, Tsuboi K, Sakae T, Sakurai H.
    • Journal Title

      Radiation Measurements

      Volume: 46 Pages: 2103-2106

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Journal Article] Direct measurement of patient's entrance skin dose during neurointerventional procedure to avoid further radiation-induced skin injuries2010

    • Author(s)
      Hayakawa M, Moritake T, Kataoka F, Takigawa T, Koguchi Y, Miyamoto Y, Akahane K, Matsumaru Y.
    • Journal Title

      Clin Neurol Neurosurg

      Volume: 112 Pages: 530-536

    • Related Report
      2012 Final Research Report
  • [Journal Article] Direct measurement of patient's entrance skin dose during neurointerventional procedure to avoid further radiation-induced skin injuries2010

    • Author(s)
      Mikito Hayakawa
    • Journal Title

      Clinical Neurology and Neurosurgery

      Volume: 112(6) Pages: 530-536

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Difference of skin dose distribution between bi-plane and single-plane systems during neurointerventional procedures2012

    • Author(s)
      Hayakawa M, Moritake T, Matsumaru Y, Kawauchi S, Koguchi Y, Miyamoto Y, Akahane K, Sakae T, Tsuboi K, Sakurai H
    • Organizer
      2012 World Congress on Medical Physics and Biomedical Engineering
    • Place of Presentation
      Beijing, China
    • Related Report
      2012 Final Research Report
  • [Presentation] X-ray shielding device for reduction of the irradiation dose to the lens during neurointerventional procedures2012

    • Author(s)
      Moritake T, Koizumi H, Matsumaru Y, Hayakawa M, Akahane K, Isobe T, Sakae T, Sakurai H, Tsuboi K
    • Organizer
      2012 World Congress on Medical Physics and Biomedical Engineering
    • Place of Presentation
      Beijing, China
    • Related Report
      2012 Final Research Report
  • [Presentation] 脳血管内治療における被ばく線量分布の検討―シングルプレーン・バイプレーン装置間比較―2012

    • Author(s)
      早川幹人、盛武敬、松丸祐司、川内覚、小口靖弘、宮本由香、赤羽恵一、榮武二、坪井康次、櫻井英幸
    • Organizer
      第28回日本脳神経血管内治療学会総会
    • Place of Presentation
      仙台
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Difference of skin dose distribution between bi-plane and single-plane systems during neurointerventional procedures2012

    • Author(s)
      Hayakawa M
    • Organizer
      2012 World Congress on Medical Physics and Biomedical Engineering
    • Place of Presentation
      北京
    • Related Report
      2012 Annual Research Report
  • [Presentation] X-ray shielding device for reduction of the irradiation dose to the lens during neurointerventional procedures2012

    • Author(s)
      Moritake T
    • Organizer
      2012 World Congress on Medical Physics and Biomedical Engineering
    • Place of Presentation
      北京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 眼球水晶体遮蔽装置の開発と効果の検証2011

    • Author(s)
      大山高一, 盛武敬, 松丸祐司, 他
    • Organizer
      第26回日本脳神経血管内治療学会総会
    • Place of Presentation
      幕張
    • Year and Date
      2011-11-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] 眼球水晶体遮蔽装置の開発と効果の検証2011

    • Author(s)
      大山高一、盛武敬、松丸祐司、小泉洋人、磯辺智範、高橋英希、赤羽恵一、早川幹人、宮本俊男、鶴岡伊知郎、渡邊和洋、坪井康次
    • Organizer
      第27回日本脳神経血管内治療学会総会
    • Place of Presentation
      幕張
    • Related Report
      2012 Final Research Report
  • [Presentation] 脳血管IVRにおける水晶体被ばく低減システムの開発とその効果の検証2010

    • Author(s)
      高橋英希、磯辺智範、盛武敬、大山高一、小泉洋人、赤羽恵一、早川幹人、松丸祐司、榮武二
    • Organizer
      第100回日本医学物理学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] Precise mapping of entrance skin dose during neurointerventional procedure: what is the most effective method to avoid radiation-induced skin injury?2010

    • Author(s)
      Moritake T, Hayakawa M, Matsumaru Y, Koguchi Y, Miyamoto Y, Mizuno Y, Chida K, Akahane K, Tsuboi K, Sakae T, Sakurai H.
    • Organizer
      The 56th Annual Meeting of Radiation Research Society in USA
    • Place of Presentation
      Maui, Hawaii, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Precise mapping of entrance skin dose during endovascular embolization for cerebral aneurysm to avoid radiation-induced skin injury2010

    • Author(s)
      Moritake T, Hayakawa M, Matsumaru Y, Takigawa T, Koguchi Y, Miyamoto Y, Mizuno Y, Chida K, Akahane K, Tsuboi K, Sakae T, Sakurai H.
    • Organizer
      16th International Conference on Solid State Dosimetry
    • Place of Presentation
      Sydney, Australia
    • Related Report
      2012 Final Research Report
  • [Presentation] Precise mapping of entrance skin dose during endovascular embolization for cerebral aneurysm to avoid radiation-induced skin injury2010

    • Author(s)
      Takashi Moritake, Mikito Hayakawa
    • Organizer
      16^<th> International Conference on Solid State Dosimetry
    • Place of Presentation
      Sofitel Hotel, Sydney, Australia
    • Related Report
      2010 Annual Research Report
  • [Presentation] Precise mapping of entrance skin dose during neurointerventional procedure : what is the most effective method to avoid radiation-induced skin injury?2010

    • Author(s)
      Takashi Moritake
    • Organizer
      56^<th> Annual Meeting Radiation Research Society
    • Place of Presentation
      Grand Wailea Resort Hotel, Maui, Hawaii, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脳血管IVRにおける水晶体被ばく低減システムの開発とその効果の検証2010

    • Author(s)
      高橋英希
    • Organizer
      第100回日本医学物理学会学術大会
    • Place of Presentation
      学術総合センター(東京都)
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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