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The examination of between the electrophysiological phenomenonand the dose volume histogram by carbon ion radiation exposure of the heart

Research Project

Project/Area Number 22791236
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionNagoya University (2011-2012)
National Institute of Radiological Sciences (2010)

Principal Investigator

OKADA Tohru  名古屋大学, 大学院・医学系研究科, 特任助教 (90447813)

Research Collaborator YOSHIOKA Koichiro  東海大学, 医学部, 准教授 (30246087)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords放射線治療学 / 重粒子線治療 / 不整脈 / 心筋梗塞後 / 心臓悪性腫瘍
Research Abstract

We examined 24 hours electrocardiography to the patients who received carbon ion radiation (CIR) to the mediastinum, and assessed the relation between the electrocardiographic phenomenon and the radiation dose in CIR exposure of the heart. We quantified the exposure of CIRT by using the dose-volume histogram. But there was no correlation between the presence of arrhythmia and the maximum/average dose of CIRT. In this study, one case of primary cardiac malignant tumor was registered. Our CIRT could indicate the safety and the high tumor control for this lethal disease. This result may be useful information for the treatment of this extreme rare disease which lacks of standardized strategies.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (19 results)

All 2014 2012 2011 2010

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (11 results) (of which Invited: 1 results) Book (1 results)

  • [Journal Article] AND THE WORKING GROUP FOR GENITOURINARY TUMORS, CARBON ION RADIOTHERAPY IN ADVANCED HYPOFRACTION REGIMENS FOR PROSTATE CANCER: FROM 20 TO 16 FRACTIONS2012

    • Author(s)
      TOHRU OKADA, HIROSHI TSUJI, TADASHI KAMADA, KOICHIRO AKAKURA, HIROYOSHI SUZUKI, JUN SHIMAZAKI, HIROHIKO TSUJII
    • Journal Title

      International Journal of Radiation Oncology Biology Physics

      Volume: 84 Pages: 968-972

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Carbon ion radiotherapy in advanced hypofractionated regimens for prostate cancer: From 20 to 16 fractions2012

    • Author(s)
      Okada T, Tsuji H, Kamada T, Akakura K, Suzuki H, Shimazaki J, Tsujii H and the working group for genitourinary tumors
    • Journal Title

      Int J Radiat Oncol Biol Phys

      Volume: 84 (4) Issue: 4 Pages: 968-972

    • DOI

      10.1016/j.ijrobp.2012.01.072

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CARBON ION RADIOTHERAPY IN ADVANCED HYPOFRACTION REGIMENS FOR PROSTATE CANCER : FROM 20 TO 16 FRACTIONS2012

    • Author(s)
      Tohru Okada
    • Journal Title

      International Journal of Radiation Oncology Biology Physics

      Volume: (印刷中)(in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 、重粒子線のヒト心臓照射における電気生理学的検討2011

    • Author(s)
      吉岡公一郎、網野真理、島牧義、山口恵子、中嶋美緒、岡田徹、鎌田正、出口喜昭、田邉晃久
    • Journal Title

      心臓

      Volume: 43 Pages: 30-34

    • NAID

      130002585074

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 重粒子線のヒト心臓照射における電気生理学的検討2011

    • Author(s)
      吉岡公一郎、岡田徹
    • Journal Title

      心臓

      Volume: 43 Pages: 30-34

    • NAID

      130002585074

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Carbon Ion Radiotherapy: Clinical Experiences at National Institute of Radiological Sciences (NIRS)2010

    • Author(s)
      Tohru Okada, Tadashi Kamada, Hiroshi Tsuji, Junetsu Mizoe, Masayuki Baba, Shingo Kato, Shigeru Yamada, Shinji Sugahara, Shigeo Yasuda, Naoyoshi Yamamoto, Reiko Imai, Azusa Hasegawa, Hiroshi Imada, Hiroki Kiyohara, Keiichi Jingu, Makoto Shinoto, Hirohiko Tsujii
    • Journal Title

      Journal of Radiation Research

      Volume: 51 Pages: 355-364

    • NAID

      10026563558

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Carbon Ion Radiotherapy : Clinical Experiences at National Institute of Radiological Sciences2010

    • Author(s)
      Tohru Okada
    • Journal Title

      Journal of Radiation Research

      Volume: 51(4) Pages: 355-364

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 重粒子線治療と心臓悪性腫瘍2012

    • Author(s)
      岡田 徹、石原俊一、伊藤善之、長縄慎二、今井礼子、辻比呂志、鎌田正
    • Organizer
      海外来化療フォーラム(招待講演)
    • Place of Presentation
      栄ガスビル
    • Year and Date
      2012-11-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 重粒子線治療と心臓悪性腫瘍2012

    • Author(s)
      岡田 徹、石原俊一、伊藤善之、長縄慎二、今井礼子、辻比呂志、鎌田正
    • Organizer
      藤田保健衛生大学(招待講演)
    • Place of Presentation
      藤田保健衛生大学
    • Year and Date
      2012-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 心臓悪性腫瘍に対する炭素線治療2012

    • Author(s)
      岡田徹
    • Organizer
      藤田保健衛生大学循環器内科医局会
    • Place of Presentation
      藤田保健衛生大学(招待講演)
    • Year and Date
      2012-03-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] 重粒子線治療と心臓悪性腫瘍2012

    • Author(s)
      岡田 徹、石原俊一、伊藤善之、長縄慎二、今井礼子、辻比呂志、鎌田正
    • Organizer
      名古屋大学医学部循環器内科医局会(招待講演)
    • Place of Presentation
      名古屋大学医学部附属病院
    • Year and Date
      2012-03-12
    • Related Report
      2012 Final Research Report
  • [Presentation] 心臓悪性腫瘍に対する炭素線治療2012

    • Author(s)
      岡田徹
    • Organizer
      名古屋大学医学部循環器内科医局会
    • Place of Presentation
      名古屋大学医学部附属病院(招待講演)
    • Year and Date
      2012-03-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] 重粒子線治療と心臓悪性腫瘍2012

    • Author(s)
      岡田 徹
    • Organizer
      第13回東海外来化療フォーラム
    • Place of Presentation
      栄ガスビル(名古屋)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 心臓内に発生した肉腫に対する炭素線治療2011

    • Author(s)
      岡田 徹、久保田誠司、牧紗代、中原理絵、 石原俊一、伊藤善之、長縄慎二、今井礼子、辻比呂志、鎌田正
    • Organizer
      日本放射線腫瘍学会 第24回学術大会
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2011-11-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 心臓内に発生した肉腫に対する炭素線治療2011

    • Author(s)
      岡田徹
    • Organizer
      日本放射線腫瘍学会第24回学術大会
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2011-11-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 心臓内に発生した肉腫に対する炭素線治療2011

    • Author(s)
      岡田 徹、久保田誠司、牧紗代、中原理絵、 石原俊一、伊藤善之、長縄慎二、今井礼子、辻比呂志、鎌田正
    • Organizer
      第150回日本医学放射線学会 中部地方会
    • Place of Presentation
      富山大学附属病院
    • Year and Date
      2011-06-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 心臓内に発生した肉腫に対する炭素線治療2011

    • Author(s)
      岡田徹
    • Organizer
      第150回日本医学放射線学会中部地方会
    • Place of Presentation
      富山大学附属病院
    • Year and Date
      2011-06-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] Carbon Ion Radiotherapy in Bone and Soft Tissue Sarcomas2010

    • Author(s)
      Tadashi Kamada, Shinji Sugahara, Hiroshi Tsuji, Itsuko Serizawa, Reiko Imai, Tohru Okada, Hirohiko Tsujii
    • Organizer
      Japanease-European Joint Symposium on Ion Cancer Therapy and NIRS-KI Joint Symposium on Ion-Radiation Sciences
    • Place of Presentation
      Karolinska, Sweden
    • Year and Date
      2010-09-09
    • Related Report
      2012 Final Research Report
  • [Book] 循環器疾患 最新の治療 2014-20152014

    • Author(s)
      吉川 大治
    • Publisher
      南江堂
    • Related Report
      2012 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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