| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
This research aimed to realize the quantitative analysis of PET data appropriate for early diagnoses of dementia and multicenter studies. A prototype system of the online analysis including automated definition of regions of interest(ROIs) was constructed, and clinical PET data was analyzed by using the system. The automated ROI definition was realized using the reverse deformation of anatomic standardization in MRI, and the shapes of ROIs were adjusted with the intention to reduce the influences by brain atrophies or partial volume effects. The PET data using[11C] carfentanil and[11C] PiB could be analyzed automatically and efficiently, and it suggested the feasibility of the valuable system.
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