Effect of hepatic functional reserve of statin in liver transplantation
| Project/Area Number |
22791248
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General surgery
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| Research Institution | Kyoto University |
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Principal Investigator |
IIDA Taku 京都大学, 医学研究科, 非常勤講師 (90437111)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 肝移植 / グラフト機能 / 肝再生 / 免疫抑制作用 / 肝線維化 / 肝繊維化 |
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| Research Abstract |
This study demonstrated that statin might have the reductive effect of reperfusion injury and liver fibrosis in the early phase after liver transplantation potentially. However statin didn' t have enough effects of immunosuppression after liver transplantation.
There was room in optimal dosage of statin and the modification of rat model.
It must be necessary to continue the evaluation of mechanism of statin in liver transplantation.
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Report
(3 results)
Research Products
(21 results)
