Improvement of graft regeneration with partial congestion in living donor liver transplantation

Research Project

Project/Area Number	22791269
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Digestive surgery
Research Institution	Gifu University
Principal Investigator	KIMURA Masaki 岐阜大学, 医学部・附属病院, 助教 (20422727)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000) Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000) Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords	生体肝移植 / うっ血肝 / 肝再生
Research Abstract	Hepatic venous congestion after living donor liver transplantation can cause primary non function. We evaluated the effectiveness of granulocyte-colony stimulating factor(G-CSF) for regeneration of remnant liver with venous congestion after hepatectomy in the past. But we were distressed to be established the model of living donor partial liver transplantation between rats. There were no living rats after 40% weight graft after transplantation. We have been making a model of living donor whole liver transplantation with partial congestion between rats. And we prepare for living donor liver transplantation in porcine model.

Report

(3 results)