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Detection of circulating tumor cells of hepatocellular carcinoma usingcancer stem cell markers

Research Project

Project/Area Number 22791292
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Digestive surgery
Research InstitutionKumamoto University (2010, 2012)
Kyushu University (2011)

Principal Investigator

MASUDA Toshiro  熊本大学, 医学部附属病院, 非常勤診療医師 (50551256)

Research Collaborator MIMA Kousuke  熊本大学, 医学部附属病院, 非常勤医師 (00546559)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords肝細胞癌 / CD90 / EpCAM / CD44 / 血中癌細胞 / 癌幹細胞 / Side population cell / FACS
Research Abstract

Evaluating in 17 healthy volunteers and 36 hepatocellular carcinoma patients, FACS withthe markers of CD44, CD90, and EpCAM revealed that the proportion of CD90+ / CD45- cellswere higher in the patients of hepatocellular carcinoma, especially in Stage III / IVcases. With in vitro studies, six hepatocellular carcinoma cell lines expressed any twoof cancer stem cell markers such as CD90, CD133, CD44, EpCAM, and CD13

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (59 results)

All 2013 2012 2011 2010 Other

All Journal Article (34 results) (of which Peer Reviewed: 34 results) Presentation (25 results)

  • [Journal Article] Nutritional supports and infectionsassociated with hepatic resection andliver transplantation in patients with chronic liver disease.2013

    • Author(s)
      Masuda T, Shirabe K, Yoshiya S, MotonoR, Morita K, Hashimoto N, Ikegami T,Yoshizumi T, Baba H, Maehara Y
    • Journal Title

      J Parenter Enteral Nutr

      Volume: 37 Issue: 3 Pages: 318-26

    • DOI

      10.1177/0148607112456041

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of safety in hepaticresection for hepatocellularcarcinoma while focusing on indirecthyperbilirubinemia.2013

    • Author(s)
      Masuda T, Beppu T, Nakagawa S, OkabeH, Chikamoto A, Mima K, Otao R, Hayashi H, Doi K, Ishiko T, Takamori H, Baba H
    • Journal Title

      J Hepatobiliary Pancreat Sci

      Volume: 20 Issue: 3 Pages: 370-4

    • DOI

      10.1007/s00534-012-0540-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] High CD44s expression is associatedwith the EMT expression profile andintrahepatic dissemination ofhepatocellular carcinoma after localablation therapy.2013

    • Author(s)
      Mima K, Hayashi H,Imai K, Kuroki H,Shigaki N, Nakagawa S, Okabe H,Chikamoto A, Watanabe M, Beppu T, BabaH
    • Journal Title

      J Hepatobiliary Pancreatic Surg

      Volume: 20 Issue: 4 Pages: 429-34

    • DOI

      10.1007/s00534-012-0580-0

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Standard prophylactic strategyagainst peritoneal disseminationmetastasis in gastric cancer.2013

    • Author(s)
      Ikeshima S, Kuramoto M, Shimada S,Yamamoto K, Masuda T, Miyata T,Yoshimatsu S, Urata M, Baba H
    • Journal Title

      J Cancer Ther

      Volume: 4 Issue: 01 Pages: 99-103

    • DOI

      10.4236/jct.2013.41a014

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mima K, Hayashi H, Kuroki H, NakagawaS, Okabe H, Chikamoto A, Watanabe M,Beppu T, Baba H2013

    • Author(s)
      Mima K, Hayashi H, Kuroki H, NakagawaS, Okabe H, Chikamoto A, Watanabe M,Beppu T, Baba H
    • Journal Title

      Oncology Lett

      Volume: 5 Issue: 1 Pages: 149-154

    • DOI

      10.3892/ol.2012.954

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] CYLD down-regulation might berelated to tumor development in HCCpatients.2013

    • Author(s)
      Kinoshita H, Okabe H, Beppu T,Chikamoto A, Hayashi H, Imai K, MimaK, Nakagawa S, Yokoyama N, Ishiko T,Shinriki S, Jono H, Ando Y, Baba H
    • Journal Title

      Mol Clin Oncol 1

      Volume: 1 Issue: 2 Pages: 309-314

    • DOI

      10.3892/mco.2013.68

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hepatic resection combined withradiofrequency ablation for initiallyunresectable colorectal livermetastases after effectivechemotherapy is a safe procedure witha low incidence of local recurrence.2012

    • Author(s)
      Mima K, Beppu T, Chikamoto A, MiyamotoY, Nakagawa S, Kuroki H, Okabe H
    • Journal Title

      Int J Clin Oncol

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] CD44s regulates the TGF-β-mediatedmesenchymal phenotype and isassociated with poor prognosis inpatients with hepatocellularcarcinoma.2012

    • Author(s)
      Mima K, Okabe H, Ishimoto T, HayashiH, Nakagawwa S, Kuroki H, Watanabe M
    • Journal Title

      Cancer Res

      Volume: 72 Issue: 13 Pages: 3414-23

    • DOI

      10.1158/0008-5472.can-12-0299

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The expression levels of CD44v6 arecorrelated with the invasiveness ofhepatocellular carcinoma in vitro,but do not appear to be clinicallysignificant.2012

    • Author(s)
      Mima K, Okabe H, Ishimoto T, HayashiH, Nakagawa S, Kuroki H, Miyake K,Takamori H
    • Journal Title

      Oncol Lett

      Volume: 5 Issue: 5 Pages: 1047-1051

    • DOI

      10.3892/ol.2012.611

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Combined measurements of serum bileacid level and splenic volume may beuseful to noninvasively assess theportal venous pressure.2012

    • Author(s)
      Hayashi H, Beppu T, Kuroki H, NakagawaS, Mima K, Okabe H, Nitta H, Imai K,Chikamoto A, Baba H
    • Journal Title

      J Gastroenterol

      Volume: 47 Issue: 12 Pages: 1336-1341

    • DOI

      10.1007/s00535-012-0599-7

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Kinoshita H, Okabe H, Beppu T,Chikamoto A, Hayashi H, Imai K, MimaK, Nakagawa S, Ishimoto T, Miyake K,Yokoyama N, Ishiko T, Baba2012

    • Author(s)
      Kinoshita H, Okabe H, Beppu T,Chikamoto A, Hayashi H, Imai K, MimaK, Nakagawa S, Ishimoto T, Miyake K,Yokoyama N, Ishiko T, Baba
    • Journal Title

      Oncol Rep

      Volume: 29 Issue: 2 Pages: 685-9

    • DOI

      10.3892/or.2012.2162

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Identification of CXCL5/ENA-78 as afactor involved in the interactionbetween cholangiocarcinoma cells andcancer-associated fibroblasts.2012

    • Author(s)
      Okabe H, Beppu T, Ueda M, Hayashi H,Ishiko T, Masuda T, Otao R, Horlad H,Mima K, Miyake K, Iwatsuki M, Baba Y,Takamori H, Jono H, Shinriki S, AndoY, Baba H
    • Journal Title

      Int J Cancer 131

      Volume: in press Issue: 10 Pages: 2234-41

    • DOI

      10.1002/ijc.27496

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] External biliary drainage and liverregeneration after majorhepatectomy2012

    • Author(s)
      Otao R, Beppu T, Ishiko T, Mima K,Okabe H, Hayashi H, Masuda T,Chikamoto A, Takamori H, Baba H
    • Journal Title

      Br J Surg

      Volume: 99 Pages: 1569-74

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hepatic resection using a liverhanging maneuver and glissoneanpedicle transection forhepatocellular carcinoma in a patientwith situs inversus totalis2012

    • Author(s)
      Harada K, Masuda T, Beppu T, Ishiko T,Chikamoto A, Hayashi H, Okabe H, OtaoR, Tanaka H, Takamori H, Baba H
    • Journal Title

      Report of a case. Surg Today

      Volume: 42 Issue: 8 Pages: 801-804

    • DOI

      10.1007/s00595-012-0156-2

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Liver hanging maneuver decreaseblood loss and operative time in aright-side hepatectomy.2012

    • Author(s)
      Beppu T, Ishiko T, Chikamoto A, KomoriH, Masuda T, Hayashi H, Okabe H, OtaoR, Sugiyama S, Nasu J, Horino K,Takamori H, Baba H
    • Journal Title

      Hepato-Gastroenterol

      Volume: 59 Pages: 542-5

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Amount of operative blood lossaffects the long-term outcome afterliver resection for hepatocellularcarcinoma.2012

    • Author(s)
      Chikamoto A, Beppu T, Masuda T, OtaoR, Okabe H, Hayashi H, Sugiyama S,Watanabe M, Ishiko T, Takamori H, Baba H
    • Journal Title

      Hepato-Gastroenterol

      Volume: 59 Pages: 1213-6

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of the mass formingintrahepatic cholangiocarcinoma withviral hepatitis.2012

    • Author(s)
      Horino K, Beppu T, Kpmpri H, Masuda T,Hayashi H, Okabe H,Takamori H, Baba H
    • Journal Title

      Hepato-Gastroenterol

      Volume: 59 Pages: 1217-9

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hybrid ablation using percutaneousand endoscopic approach formulti-nodular hepatocellularcarcinomas.2012

    • Author(s)
      Masuda T, Beppu T, Muzumoto T, Ishiko T, Chikamoto A, Hayashi H, Okabe H,Otao R, Hasita H, Takamori H, Baba H
    • Journal Title

      Hepato-Gastroenterol

      Volume: 59 Pages: 836-9

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Portal vein embolization canprevent intrahepatic metastases tonon-embolized liver.2012

    • Author(s)
      Okabe K, Beppu T, Masuda T, Hayashi H,Okabe H, Komori H, Horino K, SugiyamaS, Ishiko T, Takamori H, Yamanaka T,Baba H
    • Journal Title

      Hepato-Gastroenterol

      Volume: 59 Pages: 538-41

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Laparoscopic and thoracoscopicthermal ablation for hepatocellularcarcinoma2012

    • Author(s)
      DoiK,BeppuT,IshikoT,ChikamotoA,MasudaT,TanakaH,KuramotoM,BabaH
    • Journal Title

      J Microwave Surg

      Volume: 30 Pages: 225-230

    • URL

      http://mol.medicalonline.jp/library/journal/download?GoodsID=ai1jmwse/2012/003000/033&name=0225-0230j&UserID=133.95.84.9

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fetal-type glycogen phosphorylase(FGP) expression in intestinalmetaplasia as a high risk factor of thedevelopment of gastric carcinoma.2012

    • Author(s)
      Kuramoto M, Shimada S, Ikeshima S,Yamamoto K, Masuda T, Miyata T,Yoshimatsu S, Urata M, Baba H
    • Journal Title

      Gastric Carcinoma- New Insights intoCurrent Management (edited by DanielaLazar, InTec (Vienna))

      Pages: 93-110

    • DOI

      10.5772/51793

    • ISBN
      9789535109143
    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hepatic stellate cells acceleratethe malignant behavior ofcholangiocarcinoma.2011

    • Author(s)
      DOI:10.5772/51793kabe H, Beppu T, Hayashi H, Ishiko T,Masuda T, Otao R, Shinriki S, HorladH, Jono H, Ueda M, Ando Y, Baba H
    • Journal Title

      Ann Surg Oncol

      Volume: 18 Issue: 4 Pages: 1175-84

    • DOI

      10.1245/s10434-010-1391-7

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Liver functional volumetry forportal vein embolization using anewly-developed 99mtc-galactosylhuman serum albumin scintigraphyspect-computed tomography fusionsystem.2011

    • Author(s)
      Beppu T, Hayashi H, Okabe H, Masuda T,Mima K, Sugiyama S, Horino K, Otao R,Chikamoto A, Doi K, Ishiko T, TakamoriH, Yoshida M, Shiraishi S, YamashitaY, Baba H
    • Journal Title

      J Gastroenterol

      Volume: 46 Issue: 7 Pages: 938-43

    • DOI

      10.1007/s00535-011-0406-x

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Safety and short-term therapeuticeffects of miriplatin-lipiodolsuspension in transarterialchemoembolization (TACE) forhepatocellular carcinoma.2011

    • Author(s)
      Okabe K, Beppu T, Haraoka K, Oh-UchidaY, Yamamura S, Tomiyasu S, Yamanaka T,Sano O, Masuda T
    • Journal Title

      Anticancer Res

      Volume: 31 Pages: 2983-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preoperative portal veinembolization (PVE) for patients withhepatocellular carcinoma can improveresectability and may improvedisease-free survival2011

    • Author(s)
      Okabe H, Beppu T, Ishiko T, Masuda T,Hasyashi H, Otao R, Hasta H, Okabe K,Sugiyama S, Baba H
    • Journal Title

      J Surg Oncol

      Volume: 104 Issue: 6 Pages: 641-6

    • DOI

      10.1002/jso.21928

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Laparoscopy-assisted resection ofan undiagnosed liver tumor andascending colon cancer via mini medianlaparotomy: report of a case.2011

    • Author(s)
      Mima K, Beppu T, Chikamoto A, IshikoT, Horino K, Hayashi N, Watanabe M,Takamori H, Okabe K, Yamanaka T, Baba H
    • Journal Title

      Surg Today

      Volume: 41 Issue: 12 Pages: 1633-8

    • DOI

      10.1007/s00595-010-4524-5

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Primary neuroendocrine tumor in theliver treated by hepatectomy.2011

    • Author(s)
      Mima K, Beppu T, Murata A, Otao R,Miyake K, Okabe H, Masuda T, Okabe K,Sugiyama S, Chikamoto A, Ishiko T,Takamori H, Baba H
    • Journal Title

      Surg Today

      Volume: 41 Issue: 12 Pages: 1655-60

    • DOI

      10.1007/s00595-011-4497-z

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pigmented hepatocellular adenoma:report of a case.2011

    • Author(s)
      Masuda T, Beppu T, Ikeda K, Ishiko T,Chikamoto A, Hayashi H, Okabe H, OtaoR, Takamori H, Namimoto T, Iyama K,Baba
    • Journal Title

      Surg Today

      Volume: 41 Issue: 6 Pages: 881-3

    • DOI

      10.1007/s00595-010-4344-7

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Radiofrequency ablation incombination with hepatic resectionfor colorectal liver metastases.2011

    • Author(s)
      Beppu T, Mima K, Masuda T, Okabe H,Chikamoto A, Hayashi N, Ishiko T,Takamori H, Baba H
    • Journal Title

      J Microwave Surg

      Volume: 29 Pages: 133-136

    • URL

      http://mol.medicalonline.jp/library/journal/download?GoodsID=ai1jmwse/2011/002900/020&name=0133-0136j&UserID=133.95.84.9

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Role of thermal ablation forcolorectal liver metastases in the eraof effective chemotherapy.2011

    • Author(s)
      Mima K, Beppu T, Masuda T, Otao R,Okabe H, Chikamoto A, Hayashi N,Ishiko T, Takamori H, Baba H
    • Journal Title

      Thermal Med

      Volume: 27 Pages: 1-8

    • URL

      http://mol.medicalonline.jp/library/journal/download?GoodsID=cn4thrma/2011/002701/001&name=0001-0036j&UserID=133.95.84.91

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The role of hepatic stellate cellsin the pathogenesis of hepatocellularand cholangiocarcinoma.2011

    • Author(s)
      Okabe H, Beppu T, Hayashi H, Ishiko T,Masuda T, Otao R, Horlad H, Baba H
    • Journal Title

      Eur J Clin Med OncolEur J Clin Med Oncol

      Volume: 3 Pages: 64-68

    • URL

      http://www.ejcmo.tv/wp-content/uploads/2012/12/The-Role-of-Hepatic-Stellate-Cells-in-the-Pathogenesis-ofHepatocellular-and-Cholangiocarcinoma.pdf

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preoperative tumor marker doubling time is a useful predictor of recurrence and prognosis after hepatic resection of hepatocellular carcinoma.2010

    • Author(s)
      増田稔郎
    • Journal Title

      Journal of Surgical Oncology

      Volume: 102 Pages: 490-496

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A large splenic volume may be auseful predictor for partial splenicembolization-induced liverfunctional improvement in cirrhoticpatients.

    • Author(s)
      Hayashi H, Beppu T, Masuda T, Okabe H,Imai K, Hashimoto D, Ikuta Y,Chikamoto A, Watanabe M, Baba H
    • Journal Title

      J Hepatobiliary Pancreat Sci

      Volume: (in press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tumor compression-induced portalobstruction and selectivetransarterial chemoembolizationincrease functional liver volume inthe unobstructed area, facilitatingsuccessful resection of a large HCC:a case report.

    • Author(s)
      Tokunaga R, Hayashi H, Masuda T, MimaK, Chikamoto A, Tanaka H
    • Journal Title

      Int Surg

      Volume: (in press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] CD44s regulates the TGF-β-mediatedmesenchymal phenotype and isassociated with poor prognosisin patients with hepatocellularcarcinoma.2012

    • Author(s)
      Mima K, Okabe H, Ishimoto T, HayashiH, Nakagawa S, Kuroki H, Watanabe M,Beppu T, Saya H, Baba
    • Organizer
      The 8th International symposium oncancer research and therapy
    • Place of Presentation
      東京会館 東京都
    • Year and Date
      2012-11-10
    • Related Report
      2012 Final Research Report
  • [Presentation] 長期予後からみた大腸癌肝転移に対する新規化学・分子標的治療併用肝切除の評価2012

    • Author(s)
      別府 透、今井克憲、坂本快郎、美馬浩介、岡部弘尚、新田英利、林 洋光、生田義明、 宮本裕士、 橋本大輔、 近本 亮、土居浩一、渡邊雅之、石河隆敏、馬場秀夫
    • Organizer
      第50回日本癌治療学会学術集会
    • Place of Presentation
      パシフィコ横浜 神奈川県
    • Year and Date
      2012-10-27
    • Related Report
      2012 Final Research Report
  • [Presentation] アシアロ SPECT/Ctfusion を用いた右肝切除後肝再生の検討-門脈塞栓術の有無に着目して2012

    • Author(s)
      新田英利、別府 透、林 洋光、今井克憲、中川茂樹、黒木秀幸、美馬浩介、橋本大輔、 生田義明、 近本 亮、 石河隆敏、吉田守克山下康行、馬場秀夫
    • Organizer
      第50回日本癌治療学会学術集会
    • Place of Presentation
      パシフィコ横浜 神奈川県
    • Year and Date
      2012-10-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 造影超音波を用いた経皮的および内視鏡的アプローチによるハイブリッド凝固療法2012

    • Author(s)
      新田英利、別府 透、中川茂樹、黒木秀幸、美馬浩介、今井克憲、林 洋光、中原 修、 生田義明、 近本 亮、 土居浩一、石河隆敏
    • Organizer
      JDDW 2012
    • Place of Presentation
      神戸国際展示場 兵庫県
    • Year and Date
      2012-10-12
    • Related Report
      2012 Final Research Report
  • [Presentation] 内頚静脈を用いた生体肝移植右葉グラフとの中肝静脈分枝再建の有用性についての検討2012

    • Author(s)
      宮田辰徳、 調 憲、 池上 徹、 吉屋匠平、武藤 純、間野洋平、戸島剛男、橋本真隆、森田和豊、萱島寛人、増田稔郎、吉住朋晴、馬場秀夫
    • Organizer
      第37回日本外科系連合学会学術集会
    • Place of Presentation
      九州大学医学部百年講堂・同窓会館 福岡県
    • Year and Date
      2012-06-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝細胞癌における癌幹細胞マーカーCD44 の上皮間葉形質転換(EMT)への関与2012

    • Author(s)
      美馬浩介、岡部弘尚、石本崇胤、中川茂樹、黒木秀幸、今井克憲、新田英利、生田義明、 近本 亮、 土居浩一、 高森啓史、別府 透、馬場秀夫
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      幕張メッセ国際会議場 千葉県
    • Year and Date
      2012-04-13
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝細胞癌治療における門脈塞栓術の多角的効果2012

    • Author(s)
      別府 透、近本 亮、土居浩一、今井克憲、新田英利、岡部和利、増田稔郎、岡部弘尚、石河隆敏、高森啓史、馬場秀夫
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      幕張メッセ国際会議場 千葉県
    • Year and Date
      2012-04-13
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝内胆管癌において EZH2 は癌の進展に関与する2012

    • Author(s)
      中川茂樹、岡部弘尚、別府 透、黒木秀幸、美馬浩介、新田英利、今井克憲、生田義明、中原 修、近本 亮、土居 浩一、 石河隆敏、 高森啓史、 馬場秀夫
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      幕張メッセ国際会議場 千葉県
    • Year and Date
      2012-04-13
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝内胆管癌の癌間質相互作用における CXCL5 の役割2012

    • Author(s)
      岡部弘尚、別府 透、植田光晴、石河隆敏、近本 亮、美馬浩介、中川茂樹、今井克憲、城野博史、高森啓史、安東由喜雄、馬場秀夫
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      幕張メッセ国際会議場 千葉県
    • Year and Date
      2012-04-12
    • Related Report
      2012 Final Research Report
  • [Presentation] CD44 standard isoform regulates themesenchymal phenotype inhepatocellular carcinoma cells, andassociates with a poor prognosis inpatients.2012

    • Author(s)
      Mima K, Okabe H, Ishimoto T, Beppu T,Baba H
    • Organizer
      AACR Annual Meeting 2012
    • Place of Presentation
      McCormick Place West Chicago(USA
    • Year and Date
      2012-04-03
    • Related Report
      2012 Final Research Report
  • [Presentation] Identification of CXCL5/ENA-78regulating the interaction ofcholangiocarcinoma andcancer-associated fibroblasts.2012

    • Author(s)
      Okabe H, Beppu T, Ueda M, Hayashi H,Masuda T, Mima K, Nakagawa S, MiyakeK, Yokoyama N, Baba Y, Takamori H,Ishiko T, Jono H, Shinriki S,Ando Y,Baba H
    • Organizer
      AACR Annual Meeting 2012
    • Place of Presentation
      McCormick Place West Chicago(USA)
    • Year and Date
      2012-04-01
    • Related Report
      2012 Final Research Report
  • [Presentation] Multiple utilities of portal veinembolization for patients withhepatocellular carcinoma.2012

    • Author(s)
      Beppu T, Okabe H, Okabe K, Masuda T,Mima K, Imai K, Hayashi H, Doi K,Chikamoto A, Ishiko T, Takamori H,Baba H
    • Organizer
      ASCO 2012 Gastrointestinal CancersSymposium
    • Place of Presentation
      The Moscone WestBuilding San Francisco(USA)
    • Year and Date
      2012-01-20
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝細胞癌における癌幹細胞マーカーCD44の上皮間葉形質転換(EMT)への関与2012

    • Author(s)
      美馬浩介
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      幕張メッセ国際会議場
    • Related Report
      2012 Annual Research Report
  • [Presentation] 切除不能大腸癌肝転移の ConversionTherapy におけるラジオ波凝固療法の有用性2011

    • Author(s)
      美馬浩介、別府 透、馬場秀夫
    • Organizer
      JDDW2011
    • Place of Presentation
      福岡サンパレス 福岡県
    • Year and Date
      2011-10-22
    • Related Report
      2012 Final Research Report
  • [Presentation] Preoperative portal veinembolization can improve disease-freesurvival for patients withhepatocellular carcinoma.2011

    • Author(s)
      Beppu T,Chikamoto A, Baba H, Masuda T,Okabe H, Mima K, Ishiko T, Takamori H
    • Organizer
      the 8th International Symposium onMinimal Residual Cancer
    • Place of Presentation
      Osaka International Convention Center
    • Year and Date
      2011-09-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Preoperative portal veinembolization can improve disease-freesurvival for patients withhepatocellular carcinoma.2011

    • Author(s)
      Beppu T,Chikamoto A, Baba H, Masuda T,Okabe H, Mima K, Ishiko T, Takamori H
    • Organizer
      INTERNATIONAL SURGICAL WEEK 2011
    • Place of Presentation
      PACIFICO YOKOHAMA
    • Year and Date
      2011-08-28
    • Related Report
      2012 Final Research Report
  • [Presentation] Preoperative tumor marker doublingtime is a prognostic factorfor hepatic resection ofhepatocellular carcinoma.2011

    • Author(s)
      PACIFICO YOKOHAMA
    • Organizer
      INTERNATIONAL SURGICAL WEEK 2011
    • Place of Presentation
      PACIFICO YOKOHAMA
    • Year and Date
      2011-08-28
    • Related Report
      2012 Final Research Report
  • [Presentation] シアロ SPECT CT-fusion による分肝機能評価ー門脈塞栓術と肝切除例における有用性ー2011

    • Author(s)
      増田稔郎、別府 透、近本 亮、美馬浩介、岡部弘尚、石河隆敏、馬場秀夫、吉田守克、白石偵哉、山下康行
    • Organizer
      第66回消化器外科学会総会
    • Place of Presentation
      名古屋国際会議場 愛知県
    • Year and Date
      2011-07-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝細胞癌における CD44isoform の上皮間葉形質転換(EMT) 、癌幹細胞性への関与の解明2011

    • Author(s)
      美馬浩介、 岡部弘尚、 別府 透、 近本 亮、増田稔郎、太田尾龍、堀野 敬、高森啓史、石河隆敏、馬場秀夫
    • Organizer
      第66回日本消化器外科学会総会
    • Place of Presentation
      名古屋国際会議場 愛知県
    • Year and Date
      2011-07-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝細胞癌においてCD44isoformの上皮間葉形質転換,癌幹細胞性への関与の解明2011

    • Author(s)
      美馬浩介
    • Organizer
      第66回日本消化器外科学会総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2011-07-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高ビリルビンを呈する肝細胞癌に対する肝切除の安全性と予後2011

    • Author(s)
      増田稔郎、 別府 透、 石河隆敏、 近本 亮、岡部弘尚、 美馬浩介、 阿部真也、 中原 修、田中 洋、堀野 敬、高森啓史、馬場秀夫
    • Organizer
      日本肝胆膵外科学会・学術集会
    • Place of Presentation
      京王プラザホテル 東京都
    • Year and Date
      2011-06-10
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝切除における合併症の予防のための機能的切除率評価と最新の肝切除手技2011

    • Author(s)
      増田稔郎、 別府 透、 石河隆敏、 近本 亮、岡部弘尚、太田尾 龍、美馬浩介、阿部真也、宮田辰徳、小澄敬祐、徳永竜馬
    • Organizer
      第111回日本外科学会定期学術集会
    • Place of Presentation
      震災のため紙上発表
    • Year and Date
      2011-05-26
    • Related Report
      2012 Final Research Report
  • [Presentation] Side population cells have somestem-like properties inhepatocellular carcinoma.2011

    • Author(s)
      Okabe H, Beppu T,Ishiko T,ChikamotoA,Masuda T,Otao R,Hasita H,MimaK,Takamori H,Baba H
    • Organizer
      AACR102nd Annual Meeting 2011
    • Place of Presentation
      Orange County ConventionCenter Orlando
    • Year and Date
      2011-04-22
    • Related Report
      2012 Final Research Report
  • [Presentation] 術前CEA値に基づいた新規化学療法後の多発肝転移に対する肝切除時期の決定2010

    • Author(s)
      増田稔郎
    • Organizer
      第65回日本消化器外科学会
    • Place of Presentation
      山口 ふじ丸
    • Year and Date
      2010-07-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肝細胞癌に対するprecoagulationとhanging maneuverを用いた肝切除の有用性2010

    • Author(s)
      増田稔郎
    • Organizer
      第110回日本外科学会
    • Place of Presentation
      愛知 名古屋国際会議場
    • Year and Date
      2010-04-09
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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