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Regeneration of lesioned tract fibers in the adult brain

Research Project

Project/Area Number 22791339
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Cerebral neurosurgery
Research InstitutionShinshu University

Principal Investigator

FUKUSHIMA Nanae  信州大学, 医学部, 准教授 (90334888)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords神経再生 / 嗅覚機能 / 脳内伝導路
Research Abstract

Chondroitin sulfate proteoglycans (CSPGs) and myelin-associated proteins are known as axon-inhibitory molecules. Axonal regeneration after transection of the lateral olfactory tract (LOT), the main fiber tract of the central olfactory system, was promoted in the adult brain by degradation of CSPGs or re-transection of the naturally regenerated-LOT that consisted of unmyelinated fibers.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (15 results)

All 2013 2012 2011 2010 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (14 results)

  • [Journal Article] Moriizumi T. Analysis of spontaneous regeneration of olfactory structures with emphasis on myelination and re-innervation of cortical areas2013

    • Author(s)
      Fukushima N, Yokouchi K, Sakamoto M, Sekiguchi Y, Koike H, Kawagishi K
    • Journal Title

      Neurosci Lett

      Volume: 537 Pages: 35-39

    • DOI

      10.1016/j.neulet.2013.01.016

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Presentation] 成熟ラットにおける脳内伝導路の再生誘導2013

    • Author(s)
      福島菜奈恵, 横内久美子, 小池央, 川岸久太郎, 森泉哲次
    • Organizer
      第118回日本解剖学会
    • Place of Presentation
      高松
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 新生児期外側嗅索損傷ラットにおける伝導路の再構築2012

    • Author(s)
      福島菜奈恵, 小池央, 横内久美子, 川岸久太郎, 掛川晃, 住友深憲, 森泉哲次.
    • Organizer
      第117回日本解剖学会
    • Place of Presentation
      甲府
    • Year and Date
      2012-03-28
    • Related Report
      2012 Final Research Report
  • [Presentation] 外側嗅索再生の阻害因子に対するコンドロイチナーゼ ABC の効果2012

    • Author(s)
      小池央, 横内久美子, 川岸久太郎, 掛川晃, 住友深憲, 森泉哲次, 福島菜奈恵.
    • Organizer
      第117回日本解剖学会
    • Place of Presentation
      甲府
    • Year and Date
      2012-03-28
    • Related Report
      2012 Final Research Report
  • [Presentation] 外側嗅索再生の阻害因子に対するコンドロイチナーゼABCの効果2012

    • Author(s)
      小池央
    • Organizer
      第117回日本解剖学会
    • Place of Presentation
      山梨県甲府市
    • Year and Date
      2012-03-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新生児期外側嗅索損傷ラットにおける伝導路の再構築2012

    • Author(s)
      福島菜奈恵
    • Organizer
      第117回日本解剖学会
    • Place of Presentation
      山梨県甲府市
    • Year and Date
      2012-03-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 外側嗅索損傷新生児ラットにおいて出現する髄鞘化線維束について2011

    • Author(s)
      福島菜奈恵, 横内久美子, 平山周一, 川岸久太郎, 森泉哲次
    • Organizer
      第45回日本味と匂学会
    • Place of Presentation
      金沢
    • Year and Date
      2011-10-06
    • Related Report
      2012 Final Research Report
  • [Presentation] 外側嗅索損傷新生児ラットにおいて出現する髄鞘化線維束について2011

    • Author(s)
      福島菜奈恵
    • Organizer
      第45回日本味と匂学会
    • Place of Presentation
      石川県金沢市
    • Year and Date
      2011-10-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] Regeneration of the lateral olfactory tract in the neonatally tract-transected young adult rats2011

    • Author(s)
      福島菜奈恵, 小池央, 横内久美子, 関口泰之, 川岸久太郎, 掛川晃, 住友深憲 , 森泉哲次
    • Organizer
      第116回日本解剖学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-30
    • Related Report
      2012 Final Research Report
  • [Presentation] Induction of axonal regeneration by chondroitinase ABC in the lateral olfactory tract of adult rats2011

    • Author(s)
      小池央, 福島菜奈恵, 横内久美子, 関口泰之, 川岸久太郎, 掛川晃, 住友深憲 , 森泉哲次
    • Organizer
      第1 1 6回日本解剖学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-30
    • Related Report
      2012 Final Research Report
  • [Presentation] 新生児期外側嗅索切断ラットにおける再切断後の伝導路再生について2011

    • Author(s)
      福島菜奈恵
    • Organizer
      第116回日本解剖学会
    • Place of Presentation
      (誌上開催)
    • Year and Date
      2011-03-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] コンドロイチナーゼABCによる外側嗅索再生誘導2011

    • Author(s)
      小池央
    • Organizer
      第116回日本解剖学会
    • Place of Presentation
      (誌上開催)
    • Year and Date
      2011-03-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 外側嗅索再生へのイブプロフェンの効果2010

    • Author(s)
      関口泰之, 横内久美子, 福島菜奈恵, 川岸久太郎, 森泉哲次
    • Organizer
      Neuro 2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Related Report
      2012 Final Research Report
  • [Presentation] 外側嗅索再生へのイブプロフェンの効果2010

    • Author(s)
      関口泰之
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] 成熟ラットにおける脳内伝導路の再生誘導

    • Author(s)
      福島 菜奈恵
    • Organizer
      第118回日本解剖学会
    • Place of Presentation
      香川県高松市
    • Related Report
      2012 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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