Endothelium-Dependent Cerebral Vasodilation at Early Stage in Sepsis in Rats

• Project/Area Number: 22791424
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Anesthesiology/Resuscitation studies
• Research Institution: Gifu University
• Principal Investigator: FUKUOKA Naokazu 岐阜大学, 医学部・附属病院, 助教 (00402181)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: 敗血症性脳症 / 脳血管内皮機能 / gender

Research Abstract

Endothelium-dependent cerebral vasodilatlion is preserved at early stage in sepsis in rats. This study provides the first information of the cerebral microcirculation in a rat model of septic shock In Vivo.