Social Modulation of Pain in High-sociality Rodents.

Research Project

Project/Area Number	22791438
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Anesthesiology/Resuscitation studies
Research Institution	Kochi University (2010, 2012) Aichi Medical University (2011)
Principal Investigator	OSAKO Yoji 高知大学, 教育研究部医療学系, 准教授 (40335922)
Project Period (FY)	2010 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	痛み / 社会性 / パートナーロス / 情動 / ロストシングル / 疼痛性障害 / 社会脳 / ストレス / 医療・福祉 / 獣医学 / 行動学 / 社会的ストレス
Research Abstract	Prairie voles are high-sociality rodents, which form strong pair bonds. In this study, the voles were evaluated to verify whether social environment modulates pain cognition. Partner-lost male voles showed higher anxiety levels in novel environment, lower threshold for mechanical stimulation-induced withdrawal reflex, and exacerbation of formalin-induced nociceptive pain as compared to partner-keep males. These results suggest that social environment can modulate pain cognition through emotional changes.

Report

(4 results)