The functional and morphological study about the action mechanism of the sacral acupuncture stimulus to overactive bladder model rats.

Research Project

Project/Area Number	22791503
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Urology
Research Institution	Meiji University of Integrative Medicine
Principal Investigator	HINO Kokoro 明治国際医療大学, 鍼灸学部, 助教 (30555652)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	仙骨部鍼刺激 / ラット / 頻尿 / 膀胱機能
Research Abstract	This study of functional morphology was performed to investigate the action mechanism of the acupuncture for the transfer system of desire-to-void using overactive bladder model rats. The intercontraction interval was increased immediately after sacral acupuncture stimulation in acetic acid-induced bladder irritation rats and chloride-induced cystitis rats. And we observed the change of the recovery course of bladder mucosa by performing a sacral acupuncture. Sacral acupuncture stimulus is effective in improving urinary frequency by different action mechanism from medication, and can expect the effect on the overactive bladder of tolerance.

Report

(3 results)