Risk Evaluation of post-molar pregnancy by p57KIP2 immunohistochemistry

• Project/Area Number: 22791514
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Obstetrics and gynecology
• Research Institution: Chiba University
• Principal Investigator: KIHARA Maki 千葉大学, 医学部・附属病院, 助教 (20375760)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 胞状奇胎

Research Abstract

In order to evaluate the post molar persistent diseases, we examined the DNA profile in abnormal conceptions. From the result of 28 cases, Heterozygous CHM had a higher risk for GTN than homozygous CHM.

Research Products

• [Journal Article] Molecular distinction of consecutive molar pregnancies (2011)
  • Author(s): Usui H, Kaku H, Kihara M, Shozu M
  • Journal Title: Obstet Gynecol Volume: 117巻(2,Part 2) Pages: 492-495
  • Peer Reviewed
• [Journal Article] The risk of post-molar gestational trophoblastic neoplasia is higher in heterozygous than in homozygous complete hydatidiform moles (2010)
  • Author(s): B. Baasanjav, H. Usui, M. Kihara, H. Kaku, E. Nakada, S.Tate, A. Mitsuhashi, H. Matsui, M. Shozu
  • Journal Title: Hum Reprod Volume: 25巻5号 Pages: 1183-91
  • Peer Reviewed
• [Journal Article] The risk of post-molar gestational trophoblastic neoplasia is higher in heterozygous than in homozygous complete hydatidiform moles. (2010)
  • Author(s): Baasanjav B, Usui H, Kihara M, Kaku H, Nakada E, Tate S, Mitsuhashi A, Matsui H, Shozu M.
  • Journal Title: Human Reproduction Volume: 25 Pages: 1183-1191
  • Peer Reviewed
• [Presentation] 雄核発生全奇胎の超音波像:部分奇胎と鑑別困難な超音波像を示す例が少なくない (2011)
  • Author(s): 木原真紀, 碓井宏和, 楯真一, 加来博志, 藤田真紀, 三橋暁, 長田久夫, 生水真紀夫
  • Organizer: 第63回日本産科婦人科学会学術講演会
  • Place of Presentation: 大阪
  • Year and Date: 2011-08-29
• [Presentation] 雄核発生全奇胎の超音波像:部分奇胎と鑑別困難な超音波像を示す例が少なくない (2011)
  • Author(s): 木原真紀, 碓井宏和, 楯真一, 加来博志, 藤田真紀, 三橋暁, 長田久夫, 生水真紀夫
  • Organizer: 第63回日本産科婦人科学会学術講演会
  • Place of Presentation: リーガロイヤルホテル大阪
  • Year and Date: 2011-08-29
• [Presentation] p57KIP2免疫染色の有用性:肉眼・組織診断では雄核発生全奇胎の見逃しがある (2010)
  • Author(s): 木原真紀, 碓井宏和, 加来博志, 植原貴史, 金谷裕美, 川野みどり, 田中宏一, 長田久夫, 生水真紀夫
  • Organizer: 第62回日本産科婦人科学会学術講演会
  • Place of Presentation: 東京
  • Year and Date: 2010-04-23