Identification and expression analysis of the immunosuppressive molecule of endometrial cancer

• Project/Area Number: 22791544
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Obstetrics and gynecology
• Research Institution: Keio University
• Principal Investigator: HIRAO Nobumaru 慶應義塾大学, 医学部, 共同研究員 (80327593)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 子宮体癌 / 免疫抑制 / MYEOV / 免疫応答 / 免疫逃避 / B7-タンパ

Research Abstract

Myeloma overexpressed gene (MYEOV) was identified as a potential cancer antigen that was expressed frequently in cancer tissues. A high expression level of MYEOV was positively correlated with deep myometrial invasion and negatively correlated with diseas

Research Products

• [Journal Article] Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer. (2012)
  • Author(s): Okabayashi K, Fujita T, Miyazaki J, Okada T, Iwata T, Hirao N, Noji S, Tsukamoto N, Goshima N, Hasegawa H, Takeuchi H, Ueda M, Kitagawa Y, Kawakami Y.
  • Journal Title: Cancer Sci Volume: 103(9) Issue: 9 Pages: 1617-24
  • DOI: 10.1111/j.1349-7006.2012.02355.x
  • Peer Reviewed
• [Presentation] SEREX法により同定された癌抗原MYEOV (myeloma overexpressed gene)の発現は子宮体癌において予後と相関する (2011)
  • Author(s): 平尾薫丸, 岩田卓, 藤井多久磨, 西尾浩, 塚崎克己, 藤田知信, 河上裕, 青木大輔, 吉村泰典
  • Organizer: 第63回日本産科婦人科学会学術講演会
  • Place of Presentation: 大阪国際会議場(大阪府)
  • Year and Date: 2011-08-29
• [Presentation] SEREX 法により同定された癌抗原 MYEOV(myeloma overexpressed gene)の発現は子宮体癌において予後と相関する (2011)
  • Author(s): 平尾 薫丸, 岩田 卓, 藤井 多久磨, 西尾 浩, 塚崎 克己, 藤田 知信, 河上 裕, 青木 大輔, 吉村 泰典
  • Organizer: 第63回日本産科婦人科学会総会学術集会
  • Place of Presentation: 大阪