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Fundamental study on the pathogenesis of swallowing disorders due to aging and disuse syndrome

Research Project

Project/Area Number 22791573
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionThe University of Tokyo

Principal Investigator

NITO Takaharu  東京大学, 医学部附属病院, 講師 (60334372)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords嚥下障害 / 嚥下関連筋 / 老化 / 廃用症候群 / 性ホルモン / 嚥下 / 廃用 / ホルモン
Research Abstract

To elucidate the pathogenesis of swallowing disorders due to aging, we investigated theinfluence of sex hormones on the tongue and pharyngeal muscles using various mousemodels and immunohistochemical methods. There was no significant difference in theexpression of sex hormone receptors such as androgen and estrogen between youngand aged mouse groups.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (8 results)

All 2013 2012 2011 2010

All Journal Article (2 results) Presentation (6 results)

  • [Journal Article] 老化に伴う嚥下障害の評価と予防2011

    • Author(s)
      二藤隆春、山岨達也
    • Journal Title

      アンチ・エイジング医学

      Volume: 7(2) Pages: 202-207

    • Related Report
      2012 Final Research Report
  • [Journal Article] 医療現場からの食介護-耳鼻咽喉科医の立場から-摂食・嚥下障害を考える2011

    • Author(s)
      二藤隆春
    • Journal Title

      第5集国立健康栄養研究所

      Pages: 24-27

    • Related Report
      2012 Final Research Report
  • [Presentation] 摂食・嚥下のメカニズムと評価方法2013

    • Author(s)
      二藤隆春
    • Organizer
      日野市NST研究会
    • Place of Presentation
      東京
    • Year and Date
      2013-06-13
    • Related Report
      2012 Final Research Report
  • [Presentation] Surgicalmanagement of intractable aspiration - survey of the effectiveness of surgery using questionnaire-.2012

    • Author(s)
      Takaharu Nito
    • Organizer
      2nd European Society of swallowing disoreders.
    • Place of Presentation
      Barcelona
    • Year and Date
      2012-10-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 嚥下障害の基礎から臨床耳鼻咽喉科医が実践する治療の実際2011

    • Author(s)
      二藤隆春
    • Organizer
      第56回日本音声言語医学会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 口腔・咽喉頭の老化とアンチエイジング嚥下のアンチエイジング2011

    • Author(s)
      二藤隆春
    • Organizer
      第11回日本抗加齢医学会学術講演会
    • Place of Presentation
      京都
    • Year and Date
      2011-05-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 医療現場からの食介護-耳鼻咽喉科医の立場から2010

    • Author(s)
      二藤隆春
    • Organizer
      第5回食介護研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-12-04
    • Related Report
      2012 Final Research Report
  • [Presentation] 脳血管障害による嚥下障害への対応-耳鼻咽喉科の立場から2010

    • Author(s)
      二藤隆春
    • Organizer
      第55回日本音声言語医学会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-15
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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