| Project/Area Number |
22791574
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KARINO Shotaro 東京大学, 医学部附属病院, 助教 (00334376)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 周波数情報 / 時間情報 / 聴覚 / 聴覚皮質 / 脳幹 |
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| Research Abstract |
Auditory system has acute sensitivity to interaural time differences (ITDs). In the brainstem, a binaural cell is maximally active when the ITD is compensated by an internal delay, which brings the inputs from left and right ears in coincidence, and which would arise from axonal branching patterns of monaural input fibers. By arranging these patterns in systematic and opposite ways for the ipsilateral and contralateral inputs, ITD is transformed into a spatial activation pattern along the binaural nucleus. The dichotic presentation of two sinusoids with a slight difference in frequency elicits subjective fluctuations called binaural beat (BB). BBs provide a classic example of binaural interaction considered to result from neural interaction in the central auditory pathway that receives input from both ears. Spectral analyses of the magnetic fields revealed that the responses evoked by BBs contained a specific spectral component of BB frequency, and the magnetic fields were confid to represent an auditory steady-state response (ASSR) to BB. Our findings confirm that the activity of the human cerebral cortex can be synchronized with slow BB by using temporal information. Temporal information of acoustic signals has a critical role also in auditory recognition of consonants when it is interfered with noise loaded from various directions.
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