Neural Circuit in the Auditory Brainstem

• Project/Area Number: 22791593
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Otorhinolaryngology
• Research Institution: Shiga University of Medical Science
• Principal Investigator: TAKI Kousuke 滋賀医科大学, 医学部, 助教 (20359772)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 耳科学 / 中枢 / 聴覚 / 下丘 / 下行性投射 / シンドビスウイルス / GFP / シナプス / 数理解析 / vGluT

Research Abstract

Auditory specific mechanism of neuronetwork is searched for through visualization of synapse formation in inferior colliculus with pre-and-post synaptic element by tracer technique and synapse-specific proteins, vesicular glutaminase transporters. Sindbis virus vector mediated GFP induction as a trial for presynaptic labeling revealed remarkable projection from auditory neocortex into nucleus brachium of inferior colliculus and dorsal or external cortex of inferior colliculus with notable pattern, which is now mathematically analized

Research Products

• [Journal Article] Performance evaluation of high-resolution ultrasound imaging methods for practical use in conventional device (2013)
  • Author(s): Kousuke Taki, Hirofumi Taki, Makoto Yamakawa, Tsuyoshi Shiina, Toru Sato and Motoi Kudo
  • Journal Title: Proc. Auditory Res. Meeting, The Acoustical Society of Japan Volume: 43 Pages: 161-167
  • NAID: 40019703413
• [Journal Article] 高分解能超音波イメージング法の評価 －従来型診断装置での実用をめざして－ (2013)
  • Author(s): 瀧 公介
  • Journal Title: Proc. Auditory Res. Meeting, The Acoustical Society of Japan Volume: 印刷中
  • NAID: 40019703413
• [Journal Article] Golgi like staining of corticofugal axon terminals in the auditory brainstem of the rat, Proc. Auditory Res. Meeting (2012)
  • Author(s): Kousuke Taki, Motoi Kudo, Yoshinari Aimi, Satoru Honma, Fuduki Inoguchi, Tomoko Kimura and Miki Nishimura
  • Journal Title: The Acoustical Society of Japan Volume: 42 Pages: 299-301
• [Journal Article] High range resolution ultrasonographic vascular imaging using frequency domain interferometry with the Capon method (2012)
  • Author(s): Hirofumi Taki, Kousuke Taki, Takuya Sakamoto, Makoto Yamakawa, Tsuyoshi Shiina, Motoi Kudo and Toru Sato
  • Journal Title: IEEE Trans Med Imaging Volume: 31
  • Peer Reviewed
• [Journal Article] Golgi like staining of corticofugal axon terminals in the auditory brainstem of the rat, Proc. Auditory Res. Meeting, The Acoustical Society of Japan (2012)
  • Author(s): Kousuke Taki
  • Journal Title: Proc. Auditory Res. Meeting, The Acoustical Society of Japan Volume: 42 Pages: 299-302
• [Journal Article] High Range Resolution Ultrasonographic Vascular Imaging Using Frequency Domain Interferometry with the Capon Method (2012)
  • Author(s): H.Taki, K.Taki, T.Sakamoto, M.Yamakawa, T.Shi ina, M.Kudo, T.Sato
  • Journal Title: IEEE Trans.Med.Imaging Volume: 31 Issue: 2 Pages: 417-429
  • DOI: 10.1109/tmi.2011.2170847
  • Peer Reviewed
• [Presentation] Real-time high-range- resolution imaging method with accurate intensity estimation technique for vascular ultrasound imaging (2013)
  • Author(s): Hirofumi Taki, Takuya Sakamoto, Makoto Yamakawa, Tsuyoshi Shiina, Toru Sato, Kousuke Taki and Motoi Kudo
  • Organizer: IEEE US 2013(2013 IEEE-UFFC joint symposia)
  • Place of Presentation: プラハ(ハンガリー
• [Presentation] Real-time high- resolution vascular ultrasound using frequency domain interferometry with the ROI-division proces (2013)
  • Author(s): Hirofumi Taki, Takuya Sakamoto, Kousuke Taki, Makoto Yamakawa, Tsuyoshi Shiina, Motoi Kudo, Toru Sato
  • Place of Presentation: 大阪市
• [Presentation] Ring formation of the internal iliac artery: a risk for pelvic bleeding control (2013)
  • Author(s): Motoi Kudo, Satoru Honma, Aimi Yoshinari, Kousuke Taki, Jun Utagawa
  • Organizer: European joint congress of clinical anatomy 2013
  • Place of Presentation: リスボン(ポルトガル)
• [Presentation] 聴覚関連領域からの下行性投射系の形態学的解析 (2013)
  • Author(s): 瀧 公介, 相見 良成, 井之口 文月, 木村 智子, 西村 美紀, 本間 智, 工藤基
  • Organizer: Neuro2013(第36回日本神経科学大会)
  • Place of Presentation: 京都市
• [Presentation] 工藤基下丘外側皮質から視蓋前域ー中脳網様体への投射 (2013)
  • Author(s): 井之口 文月, 瀧 公介, 玉川 俊広, 木村 智子, 西村 美紀, 本間 智
  • Organizer: Neuro2013(第36回日本神経科学大会)
  • Place of Presentation: 京都市
• [Presentation] 聴覚伝導路は2つのシステムからなる:下丘外側核から視蓋前域ー中脳網様体への投射 (2013)
  • Author(s): 井之口 文月, 瀧 公介, 木村 智子, 西村 美紀, 玉川 俊広, 本間 智, 松田 和郎, 工藤 基
  • Organizer: 第118回日本解剖学会全国学術集会
  • Place of Presentation: 香川県高松市
• [Presentation] 聴覚伝導路は２つのシステムからなる：下丘外側核から視蓋前域ー中脳網様体への投射 (2013)
  • Author(s): 井之口 文月
  • Organizer: 第118回日本解剖学会全国学術集会
  • Place of Presentation: 香川県高松市
• [Presentation] 聴覚関連領域からの下行性投射系の形態学的解析 (2013)
  • Author(s): 瀧 公介
  • Organizer: Neuro2013（第36回日本神経科学大会）
  • Place of Presentation: 京都市
• [Presentation] 下丘外側皮質から視蓋前域ー中脳網様体への投射 (2013)
  • Author(s): 井之口 文月
  • Organizer: Neuro2013（第36回日本神経科学大会）
  • Place of Presentation: 京都市
• [Presentation] Real-Time High-Resolution Vascular Ultrasound Using Frequency Domain Interferometry with the ROI-Division Process (2013)
  • Author(s): Hirofumi Taki
  • Organizer: 35th Annual International IEEE EMBS Conference
  • Place of Presentation: 大阪市
• [Presentation] Axon terminals of the cortico-collicular projection in the rat auditory system (2012)
  • Author(s): 瀧公介, 相見良成, 井之口文月, 木村智子, 西村美紀, 本間智, 工藤基
  • Organizer: 第117回日本解剖学会全国学術集会
  • Place of Presentation: 山梨大学甲府キャンパス(山梨県)
  • Year and Date: 2012-03-27
• [Presentation] Dual system of ascending auditory pathways: Projection from external nucleus of inferior colliculus to pretectum and midbrain retivular formation (2012)
  • Author(s): 井之口 文月, 木村 智子, 西村 美紀, 玉川 俊広, 本間 智, 瀧 公介, 工藤基
  • Organizer: The 17th Auditory Research Forum
  • Place of Presentation: 滋賀県大津市
• [Presentation] ラット大脳皮質聴覚野後背側領域からの下行性投射軸索終末の解析 (2012)
  • Author(s): 瀧 公介, 相見 良成, 井之口 文月, 木村 智子, 西村 美紀, 本間 智, 工藤基
  • Organizer: Neuro2012(第35回日本神経科学大会)
  • Place of Presentation: 名古屋市
• [Presentation] High-resolution vascular ultrasound imaging for accurate measurement of carotid intima-media thickness (2012)
  • Author(s): Hirofumi Taki, Takuya Sakamoto, Kousuke Taki, Makoto Yamakawa, Tsuyoshi Shiina, Motoi Kudo and Toru Sato
  • Organizer: ESC2012
  • Place of Presentation: ミュンヘン(ドイツ)
• [Presentation] Axon terminals of the corticocollicular projection in the rat auditory system (2012)
  • Author(s): 瀧 公介, 相見 良成, 井之口 文月, 木村 智子, 西村 美紀, 本間 智, 工藤基
  • Organizer: 第117回日本解剖学会全国学術集会
  • Place of Presentation: 山梨県甲府市
• [Presentation] High-resolution vascular ultrasound imaging for accurate measurement of carotid intima-media thickness (2012)
  • Author(s): Hirofumi Taki
  • Organizer: ESC2012
  • Place of Presentation: ミュンヘン（ドイツ）
• [Presentation] ラット大脳皮質聴覚野後背側領域からの下行性投射軸索終末の解析 (2012)
  • Author(s): 瀧 公介
  • Organizer: Neuroscience2012（第35回日本神経科学大会）
  • Place of Presentation: 名古屋市
• [Presentation] High range resolution ultrasound imaging of a human carotid artery using frequency domain interferometry (2011)
  • Author(s): Taki H, Sakamoto T, Taki K, Yamakawa M, Shiina T, Kudo M, Sato T
  • Organizer: IEEE International Ultrasonics Symposium 2011
  • Place of Presentation: Caribe Royale, Orlando, Florida, USA
  • Year and Date: 2011-10-21
• [Presentation] 周波数領域干渉計法を用いた医用超音波血管イメージング法の血管壁境界描出能 (2011)
  • Author(s): 瀧宏文、瀧公介、阪本卓、山川誠、椎名毅、工藤基、佐藤亨
  • Organizer: 日本超音波医学会第84回学術集会
  • Place of Presentation: グランドプリンスホテル新高輪国際館パミール(東京都)
  • Year and Date: 2011-05-28
• [Presentation] High range resolution ultrasound imaging of a human carotid artery using frequency domain interferometry (2011)
  • Author(s): Hirofumi Taki, Takuya Sakamoto, Kousuke Taki, Makoto Yamakawa, Tsuyoshi Shiina, Motoi Kudo and Toru Sato
  • Organizer: EEE International Ultrasonics Symposium 2011
  • Place of Presentation: オーランド(アメリカ、フロリダ州)
• [Presentation] 周 波 数領域干渉計法を用いた医用超音波血管イメージング法の血管壁境界描出能 (2011)
  • Author(s): 瀧 宏文, 瀧 公介, 阪本 卓也, 山川誠, 椎名 毅, 工藤 基, 佐藤 亨
  • Organizer: 日本超音波医学会第84回学術集会
  • Place of Presentation: 東京都
• [Presentation] High Range Resolution Ultrasonographic Vascular Imaging Using Frequency Domain Interferometry with the Capon Method (2010)
  • Author(s): 瀧宏文、瀧公介、佐藤亨, ほか
  • Organizer: 32nd Annual International Conference of the IEEE EMBC
  • Place of Presentation: ブエノスアイレス(アルゼンチン)
  • Year and Date: 2010-09-04
• [Presentation] 周波数領域干渉計法を用いた医用超音波血管イメージング法の血管壁境界描出能 (2010)
  • Author(s): 瀧宏文、瀧公介、佐藤亨, ほか
  • Organizer: 日本超音波医学会第83回学術集会
  • Place of Presentation: 京都国際会議場(京都府)
  • Year and Date: 2010-05-29
• [Presentation] 周波数領域干渉計法とCapon法を用いた超音波B-mode像の高空間分解能化 (2010)
  • Author(s): 瀧 宏文, 瀧 公介, 阪本 卓也, 山川誠, 椎名 毅, 佐藤 亨
  • Organizer: 日本超音波医学会第83回学術集会
  • Place of Presentation: 京都市
• [Presentation] High Range Resolution Ultrasonographic Vascular Imaging with Frequency Domain Interferometry
  • Author(s): Hirofumi Taki, Kousuke Taki, Takuya Sakamoto, Makoto Yamakawa, Tsuyoshi Shiina, and Toru Sato
  • Organizer: 32nd Annual International Conference of the IEEE EMBC, 2010
  • Place of Presentation: ブエノスアイレス(アルゼンチン)
• [Book] 周波数領域干渉計を用いた超音波イメージング法における適切な周波数平均幅=周波数平均に用いる帯域幅と推定電力精度= (2012)
  • Author(s): 瀧 宏文, 山川 誠, 椎名 毅, 佐藤 亨, 瀧 公介, 工藤 基
  • Publisher: 超音波テクノ
• [Book] 超音波テクノ (2012)
  • Author(s): 瀧 宏文, 山川 誠, 椎名 毅, 佐藤 亨, 瀧 公介, 工藤 基
  • Total Pages: 4
  • Publisher: 周波数領域干渉計を用いた超音波イメージング法における適切な周波数平均幅＝周波数平均に用いる帯域幅と推定電力精度＝
• [Remarks]
  • URL: http://www.shiga-med.ac.jp/db/pub_top.php
• [Remarks] 滋賀医科大学研究情報データベース
  • URL: http://www.shiga-med.ac.jp/db/index.php
• [Remarks]
• [Remarks]
  • URL: http://www.shiga-med.ac.jp/db/pub_top.php