Estimation of prognosis by three-dimensional analysis of positional nysgatgmus in patients with benign paroxysmal positional vertigo

• Project/Area Number: 22791597
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Otorhinolaryngology
• Research Institution: Osaka University
• Principal Investigator: IMAI Takao 大阪大学, 医学系・研究科, 助教 (80570663)
• Co-Investigator(Renkei-kenkyūsha): UNO Atsuhiko 大阪大学, 医学系・研究科, 講師 (10335341) ; NAKAMAE Koji 大阪大学, 情報科学研究科, 教授 (40155809)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2011: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000); Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 良性発作性頭位めまい症 / 方向交代性上向性眼振 / 眼球運動三次元解析 / 速度蓄積機構 / 小脳腫瘍 / 問診 / 三半規管 / 病的眼振 / 上眼瞼向き眼振 / 異常眼球運動 / 眼球運動解析三次元解析 / ビデオ眼振図計 / 赤外線CCDカメラ

Research Abstract

We have studied the natural course of positional vertigo in patients with the apogeotropic variant of horizontal canal type of benign paroxysmal positional vertigo(AH-BPPV) and showed the natural course of AH-BPPV is not refractory. In patients with benign paroxysmal positional vertigo, when the axis of eye rotation during abnormal nystagmus is perpendicular to the plane of semicircular canal, the prognosis is good, and when the axis is not perpendicular to the plane of semicircular canal, the prognosis is not good.

Research Products

• [Journal Article] Benign paroxysmal positional vertigo showing sequential translations of four types of nystagmus (2012)
  • Author(s): Imai T, Takeda N, Uno A, Horii A, Kitahara T, Nishiike S, Higashi-Shingai K, Inohara H
  • Journal Title: Auris Nasus Larynx Volume: (in press)
  • Peer Reviewed
• [Journal Article] Diagnosis of the subtype and affected ear of benign paroxysmal positional vertigo using a questionnaire (2012)
  • Author(s): Higashi-Shingai K, Imai T, Kitahara T, Uno A, Ohta Y, Horii A, Nishiike S, Kawashima T, Hasegawa T, Inohara H
  • Journal Title: Acta Otolaryngologica Volume: (in press)
  • Peer Reviewed
• [Journal Article] 3D analysis of spontaneous upbeat nystagmus in a patient with astrocytoma in cerebellum (2012)
  • Author(s): Higashi-Shingai K, Imai T, Takeda N, Uno A, Nishiike S, Horii A, Kitahara T, Fuse Y, Hashimoto M, Senba O, Suzuki T, Fujita T, Otsuki H, Inohara H
  • Journal Title: Auris Nasus Larynx Volume: 39 Pages: 216-219
  • Peer Reviewed
• [Journal Article] Implication of substance P neuronal system in the amygdala as a possible mechanism for hypergravily-induced motion sickness (2012)
  • Author(s): Horii A, Nakagawa A, Uno A, Kitahara T, Imai T, el al
  • Journal Title: Brain Research Volume: 1435 Pages: 91-98
  • Peer Reviewed
• [Journal Article] Natural course of positional vertigo in patients with apogeotropic variant of horizontal canal benign paroxysmal positional vertigo (2011)
  • Author(s): Imai T, Takeda N, Ito M, Inohara H
  • Journal Title: Auris Nasus Larynx Volume: 38 Pages: 2-5
  • Peer Reviewed
• [Journal Article] Benign paroxysmal positional vertigo showing sequential translations of four types of nystagmus (2011)
  • Author(s): T imai, Takeda N, Uno A, et al
  • Journal Title: Auris Nasus Larynx
  • Peer Reviewed
• [Journal Article] Diagnosis of the subtype and affected ear of benign paroxysmal positional vertigo using a questionnaire (2011)
  • Author(s): Higashi-Shingai K, Imai T, et al
  • Journal Title: Auris Nasus Larynx Volume: 131 Pages: 1264-1269
  • Peer Reviewed
• [Journal Article] Low-tone air-bone gaps after endolymphatic sac surgery (2011)
  • Author(s): Kitahara T, Horii A, Mishiro Y, Kawashima T, Imai T, et al
  • Journal Title: Auris Nasus Larynx Volume: 38 Pages: 178-184
  • Peer Reviewed
• [Journal Article] Transient low-tone air-bone gaps during convalescence immediately after canal plugging surgery for BPPV (2011)
  • Author(s): Uetsuka S, Kitahara T, Horii A, Imai T, et al
  • Journal Title: Auris Nasus Larynx
  • Peer Reviewed
• [Journal Article] Changes in beta 2 adrenergie receptor and AMP-activated protein kinase alphe-2 rubunit in the rat veatibular norve after labyrinthectomy (2011)
  • Author(s): Kitahara T, Horii A, Uno A, Imai T, et al
  • Journal Title: Neuroscience Research Volume: 72 Pages: 221-226
  • Peer Reviewed
• [Journal Article] Endolymphatic hydrops in Meniere's disease detected by MRI after intratympanic administration of gadolinium : Comparison with sudden deafness. (2011)
  • Author(s): Horii A, Imai T, et al.
  • Journal Title: Acta Oto-laryngologica Volume: (In press)
  • Peer Reviewed
• [Journal Article] A case of apogeotropic nystagmus with brainstem lesion : An implication for mechanism of central apogeotropic nystagmus (2010)
  • Author(s): Imai T, Horii A, Takeda N, Kitahara T, Higashi-Shingai K, Inohara H
  • Journal Title: Auris Nasus Larynx Volume: 37 Pages: 742-746
  • Peer Reviewed
• [Journal Article] Expression and translocation of aquaporin-2 in the endolymphatic sac in patients with Meniere's disease (2010)
  • Author(s): Maekawa C, Imai T, et al.
  • Journal Title: Journal of Neuroendocrinology Volume: 22 Pages: 1157-1164
  • Peer Reviewed
• [Presentation] Differential Diagnosis of True and'Pseudo' Anterior canal Benign Paroxymal Positional Vertigo (2011)
  • Author(s): Imai T、Masumura C、Takeda N、Kitahara T、Uno A、Nishiike S、Horii A、Inohara H
  • Organizer: Japna-Taiwan conference on Otolaryngology-Head and Neck Surgery
  • Place of Presentation: 神戸大学
  • Year and Date: 2011-12-09
• [Presentation] Differential diagnosis of true and pseudo anterior canal benign paroxysmal positional vertigo (2011)
  • Author(s): T Imai, C Masumura, et al
  • Organizer: 11^<th> Japan-Taiwan conference on Otolaryngology-Head and Neck Surgery
  • Place of Presentation: 兵庫県神戸市
  • Year and Date: 2011-12-09
• [Presentation] BPPVの患側とサブタイプを問診だけでどの程度診断できるか (2011)
  • Author(s): 岩本依子、今井貴夫、真貝佳代子、北原糺、宇野敦彦、西池季隆、堀井新、猪原秀典
  • Organizer: 日本めまい平衡医学学会
  • Place of Presentation: 東邦大学
  • Year and Date: 2011-11-18
• [Presentation] 偏中心性回転を用いた耳石器機能の検討 (2011)
  • Author(s): 滝本泰光、今井貴夫、武田憲昭、宇野敦彦、西池季隆、堀井新、北原糺、岡崎鈴代、鎌倉武史、肥塚泉、猪原秀典
  • Organizer: 日本めまい平衡医学学会
  • Place of Presentation: 東邦大学
  • Year and Date: 2011-11-18
• [Presentation] 前半規管型良性発作性頭位めまい症と偽前半規管型良性発作性頭位めまい症の鑑別 (2011)
  • Author(s): 増村千佐子、今井貴夫、北原糺、宇野敦彦、西池季隆、堀井新、武田憲昭、猪原秀典
  • Organizer: 日本めまい平衡医学学会
  • Place of Presentation: 東邦大学
  • Year and Date: 2011-11-17
• [Presentation] 中枢性上眼瞼向き眼振と末梢性上眼瞼向き眼振の鑑別-三次元眼球運動解析による眼振の回転軸の検討- (2011)
  • Author(s): 真貝佳代子、今井貴夫、武田憲昭、宇野敦彦、西池季隆、堀井新、北原糺、猪原秀典
  • Organizer: 日本めまい平衡医学学会
  • Place of Presentation: 東邦大学
  • Year and Date: 2011-11-17
• [Presentation] 先天性眼振の240Hz眼球運動三次元解析 (2011)
  • Author(s): 今井貴夫、滝本泰光、宇野敦彦、西池季隆、堀井新、北原糺、鎌倉武史、武田憲昭、猪原秀典
  • Organizer: 日本めまい平衡医学学会
  • Place of Presentation: 東邦大学
  • Year and Date: 2011-11-17
• [Presentation] 先天性眼振の240Hz眼球運動三次元解析 (2011)
  • Author(s): 今井貴夫、滝本泰光、宇野敦彦, 他
  • Organizer: 第70回日本めまい平衡医学会総会
  • Place of Presentation: 千葉県千葉市
  • Year and Date: 2011-11-17
• [Presentation] エプリー法で治療した後に前半規管型良性発作性頭位めまい症に変化したと思われる眼振の責任半規管の同定 (2010)
  • Author(s): 今井貴夫、増村千佐子、宇野敦彦、西池季隆、武田憲昭、堀井新、北原糺、真貝佳代子、猪原秀典
  • Organizer: 日本めまい平衡医学会学会
  • Place of Presentation: 京都大学
  • Year and Date: 2010-11-18
• [Presentation] Epley法で治療した後に前半規管型良性発作性頭位めまい症に変化したと思われる眼振の責任半規管の同定 (2010)
  • Author(s): 今井貴夫
  • Organizer: 第69回日本めまい平衡医学会総会・学術講演会
  • Place of Presentation: 国立京都国際会館(京都)
  • Year and Date: 2010-11-18
• [Presentation] 3D analysis of benign positional nystagmus due to cupulolithiasis in posterior semicirucular canal (2010)
  • Author(s): Imai T、Uno A、Nishiike S、Kitahara T、Horii A、Takeda N、Inohara H
  • Organizer: Barany Society meeting
  • Place of Presentation: The Iceland University、Iceland
  • Year and Date: 2010-08-20
• [Presentation] 3D analysis of benign positional nystagmus due to cupulolithiasis in posterior semicircular canal (2010)
  • Author(s): Imai T, et al
  • Organizer: XXVI Barany Society Meeting
  • Place of Presentation: Reykjavik (Iceland)
  • Year and Date: 2010-08-19