Analysis of the development of spiral ganglion cells utilizingPC3-GFP knock-in mice
| Project/Area Number |
22791610
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kumamoto University |
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Principal Investigator |
YAMADA Takao 熊本大学, 医学部附属病院, 医員 (90573593)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 耳科学 / 遺伝子 / ラセン神経節 / 分化 |
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| Research Abstract |
In order to elucidate the development mechanism of cochlear spiralganglion cells, we investigated the PC3 gene. PC3 gene was expressed at the spiral ganglioncells of heterozygous PC3-GFP knock-in mice. Spiral ganglion cells were decreased inhomozygous PC3-GFP knock-in mice. The results indicate that PC3 gene is involved in thedevelopment of spiral ganglion cells.
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Report
(4 results)
Research Products
(3 results)
