| Project/Area Number |
22791623
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Wakayama Medical University |
|---|
Principal Investigator |
OGAMI Masashi 和歌山県立医科大学, 医学部, 博士研究員 (90423946)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 鼻科学 / 肺炎球菌 / 肺炎球菌共通抗原 / イムノクロマトグラフィー法 / 鼻咽腔 / リアルタイムPCR |
|---|
| Research Abstract |
Streptococcus pneumonia(S. pneumoniae) colonized in nasopharynx of children is an important pathogenic bacteria in pediatric acute otitis media and rhinosinusitis. In this study, we performed quantitative analysis of nasopharyngeal S. pneumonia by using real-time PCR method. In the healthy children, the concentration of S. pneumoniae showed an inverse relation with the age. On the other hands, the concentration of S. pneumoniae in the children with upper respiratory infection was higher than the healthy children. Moreover, we revealed that a new rapid antigen test for detection of pneumococci in middle ear fluids and nasopharyngeal secretions can be an available tool for detection S. pneumoniae.
|
