Study on the serotypes and specific immune response of Streptococcus pneumonia in acute otitis media.
| Project/Area Number |
22791624
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
IKEDA Yorihiko 和歌山県立医科大学, 医学部, 助教 (20423949)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 急性中耳炎 / 肺炎球菌 / 血清型 |
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| Research Abstract |
Streptococcus pnenmoniae is a leading cause of acute otitis media. S. pnenmoniae typically colonizes the human nasopharynx. Among 202 S. pnenmoniae isolates from the uuper respiratory tract infections(URT), we were determined serotype 19F(19. 4%), serotype 23F(14. 9%), serotype 14(11. 4%), serotype 6B(11. 4%), serotype 6A(9. 1%), serotype 3(9. 1%). All strains of serotype 3 were penicillin susceptible S. pnenmoniae(PSSP), on the other hand, strains of serotype 19F and serotype 23F were predominant in penicillin resistant S. pnenmoniae(PRSP) or penicillin intermediately resistant S. pnenmoniae(PISP). The coverage of S. pnenmoniae vaccine were 7-valent pneumococcal conjugate vaccine(7-PCV, 60. 6%), 11-PCV(61. 7%), 13-PCV(82. 9%), PPV(82. 9%) respectively.
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Report
(3 results)
Research Products
(1 results)
