Project/Area Number |
22791725
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Plastic surgery
|
Research Institution | Oita University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
Keywords | 組織培養 / 移植学 / 体外フォトフェレーシス / 同種異系間複合組織移植 / 鼠径皮弁 / 免疫抑制剤 |
Research Abstract |
We could make composite tissue allo-transplantation model using BN rat and LEW rat. Using this model, we assessed the effect of photopheresis to rejection reaction after composite tissue allo-transplantation, using clinical observation, pathological examination, and mixed lymphocyte reaction assay. As the result of our study, we could prove that photopheresis can suppress the rejection reaction after composite tissue allo-transplantation.
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