| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
Kinetic change of dermal fibroblasts of rats and differentiated PC12 cells like sympathetic ganglionic neuron was investigated under various types of negative pressure. The results indicated that proliferation and migration potencies of dermal fibroblasts were promoted under intermittent negative pressure more than under atmospheric pressure, and collagen gel including dermal fibroblasts contracted under continuous negative pressure more than under atmospheric pressure. Then, the collagen gel in which dermal fibroblasts and differentiated PC12 cells were co-cultured contracted under intermittent negative pressure more than under atmospheric pressure. The results suggested that intermittent negative pressure effectively promotes wound healing.
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