| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
The purpose of this study was to elucidate the contribution of bioactive lipid mediators to the pathogenesis of influenza virus, such as acute respiratory distress syndrome. From the results of lipid metabolome analysis, I found that some bioactive lipid molecules exhibit characteristic patterns in progression of the pathology, suggesting a possibility that these lipids alleviatethe symptoms of the infection. In addition, I propose that an influenza virus-inducible phospholipase A_2 may regulate the production of these bioactive molecules.
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