Localization of vesicular amino acid transporters in trigeminal sensory neurons

• Project/Area Number: 22791763
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Morphological basic dentistry
• Research Institution: Osaka University
• Principal Investigator: HONMA Shiho 大阪大学, 大学院・歯学研究科, 講師 (40372627)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 口腔解剖学 / シナプス小胞 / VGLUT / 三叉神経 / 歯根膜 / 口腔感覚 / 免疫組織化学 / グルタミン酸

Research Abstract

We observed mRNA and protein expression of the vesicular glutamate transporters(VGluTs) in trigeminal mesencephalic nucleus and trigeminal ganglion. In the peripheral nervous system, The mechanoreceptors in the orofacial region express VGluT1 subtype. Using electron microscopic analysis, vesicular like structure in mechanoreceptors represented VGluT1 expression

Research Products

• [Journal Article] Vesicular glutamate trnsporter immunoreactivity in the periodontal liga ment of the rat incisor (2012)
  • Author(s): Honma S, Kato A, Shi L, Yatani H, Wa kisaka S
  • Journal Title: The Anatomical Record Volume: 295巻 Pages: 160-166
  • Peer Reviewed
• [Journal Article] Vesicular glutamate trnsporter immunoreactivity in the periodontal ligament of the rat incisor (2012)
  • Author(s): Honma S, Kato A, Shi L, Yatani H, Wakisaka S
  • Journal Title: The Anatomical Record Volume: 295 Pages: 160-166
  • Peer Reviewed
• [Journal Article] 歯根膜感覚受容の形態学的神経基盤-歯根膜ルフィニ神経終末研究のトピックス (2011)
  • Author(s): 本間志保、脇坂聡
  • Journal Title: 脳21 Volume: 14巻 Pages: 380-384
• [Presentation] ラット三叉神経節および臼歯歯髄におけるSNARE蛋白質の局在 (2012)
  • Author(s): 本間志保、角野公紀、脇坂聡
  • Organizer: 第117回日本解剖学会総会・全国学術集会
  • Place of Presentation: 山梨大学(甲府)
  • Year and Date: 2012-03-27
• [Presentation] ラット三叉神経節および臼歯歯髄におけるSNARE蛋白質の局在 (2012)
  • Author(s): 本間志保、角野公紀、脇坂聡
  • Organizer: 第117回日本解剖学会総会・全国学術集会
  • Place of Presentation: 山梨大学(甲府市)
  • Year and Date: 2012-03-27
• [Presentation] ラット歯根膜機械受容器におけるイノシトール三リン酸受容体の局在 (2010)
  • Author(s): 本間志保、三木依子、脇坂聡
  • Organizer: 弟52回歯科基礎医学会学術集会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2010-09-21