Project/Area Number |
22791793
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Functional basic dentistry
|
Research Institution | Kagoshima University |
Principal Investigator |
NAKAYAMA Ayumi 鹿児島大学, 医歯学総合研究科, 助教 (10398290)
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 味覚 / 味蕾 / 細胞分化 / 発生 / 転写制御因子 / マウス / 細胞・組織 |
Research Abstract |
The relationship between the basal cell markers and Sox2, and timing of the basal cell marker appearance during development of the circumvallate papillae were analyzed. The results suggest that : 1) the beginning of taste bud development may be indicated by Prox1 expression before the expression of Shh and/or Sox2 is focused to taste bud primordia, 2) during the CV development, the onset of the basal cell marker expression in the apical epithelium precedes that in the trench wall.
|