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Function of the basal cells of taste buds during taste bud development

Research Project

Project/Area Number 22791793
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Functional basic dentistry
Research InstitutionKagoshima University

Principal Investigator

NAKAYAMA Ayumi  鹿児島大学, 医歯学総合研究科, 助教 (10398290)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords味覚 / 味蕾 / 細胞分化 / 発生 / 転写制御因子 / マウス / 細胞・組織
Research Abstract

The relationship between the basal cell markers and Sox2, and timing of the basal cell marker appearance during development of the circumvallate papillae were analyzed. The results suggest that : 1) the beginning of taste bud development may be indicated by Prox1 expression before the expression of Shh and/or Sox2 is focused to taste bud primordia, 2) during the CV development, the onset of the basal cell marker expression in the apical epithelium precedes that in the trench wall.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (14 results)

All 2011 2010 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (11 results) Remarks (1 results)

  • [Journal Article] 味蕾の発生過程における味蕾基底細胞マーカーとSox2の発現2011

    • Author(s)
      中山歩, 三浦裕仁, 大木誠, 日下部裕子, 原田秀逸
    • Journal Title

      日本味と匂学会誌

      Volume: 18巻 Pages: 223-224

    • NAID

      110009441198

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 味蕾の発生過程における味蕾基底細胞マーカーとSox2の発現2011

    • Author(s)
      中山歩
    • Journal Title

      日本味と匂学会誌

      Volume: 18 Pages: 223-224

    • NAID

      110009441198

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Basal cell markers of taste buds and Sox2 during taste bud development and maturation2011

    • Author(s)
      中山歩, 三浦裕仁, 大木誠, 日下部裕子, 原田秀逸
    • Organizer
      第9回国際シンポジウム「味覚・嗅覚の分子神経機構」
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-06
    • Related Report
      2011 Final Research Report
  • [Presentation] Basal cell markers of taste buds and Sox2 during taste bud development and maturation2011

    • Author(s)
      中山歩
    • Organizer
      第9回国際シンポジウム「味覚・嗅覚の分子神経機構」
    • Place of Presentation
      九州大学(福岡県)
    • Year and Date
      2011-11-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] Regional differences in bitter taste signal transduction between the soft palate and fungiform papillae2011

    • Author(s)
      三浦裕仁, 友成博, 中山歩, 松村江梨子, 大木誠, 原田秀逸
    • Organizer
      第9回国際シンポジウム「味覚・嗅覚の分子神経機構」
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-05
    • Related Report
      2011 Final Research Report
  • [Presentation] Regional differences in bitter taste signal transduction between the soft palate and fungiform papillae2011

    • Author(s)
      三浦裕仁
    • Organizer
      第9回国際シンポジウム「味覚・嗅覚の分子神経機構」
    • Place of Presentation
      九州大学(福岡県)
    • Year and Date
      2011-11-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] 味蕾の発生・成熟過程における味蕾基底細胞マーカーとSox2の発現2011

    • Author(s)
      中山歩, 三浦裕仁, 大木誠, 日下部裕子, 原田秀逸
    • Organizer
      日本味と匂学会第45回大会
    • Place of Presentation
      石川
    • Year and Date
      2011-10-07
    • Related Report
      2011 Final Research Report
  • [Presentation] 味蕾の発生・成熟過程における味蕾基底細胞マーカーとSox2の発現2011

    • Author(s)
      中山歩
    • Organizer
      日本味と匂学会第45回大会
    • Place of Presentation
      石川県立音楽堂(石川県)
    • Year and Date
      2011-10-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] 味蕾の発生・成熟過程における味蕾基底細胞マーカーとSox2の関連性2011

    • Author(s)
      中山歩, 三浦裕仁, 大木誠, 日下部裕子, 原田秀逸
    • Organizer
      第53回基礎歯科医学会学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] 味蕾の発生・成熟過程における味蕾基底細胞マーカーとSox2の関連性2011

    • Author(s)
      中山歩
    • Organizer
      第53回基礎歯科医学会学術大会
    • Place of Presentation
      長良川国際会議場(岐阜県)
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 味蕾の細胞分化と機能の部位特性2011

    • Author(s)
      三浦裕仁, 友成博, 中山歩, 大木誠, 原田秀逸
    • Organizer
      第53回基礎歯科医学会学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-09-30
    • Related Report
      2011 Final Research Report
  • [Presentation] 味蕾の細胞分化と機能の部位特性2011

    • Author(s)
      三浦裕仁
    • Organizer
      第53回基礎歯科医学会学術大会
    • Place of Presentation
      長良川国際会議場(岐阜県)
    • Year and Date
      2011-09-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] Appearance of Prox1 cells during taste buds development an turnover2010

    • Author(s)
      三浦裕仁, 中山歩, 大木誠, 原田秀逸
    • Organizer
      第8回国際シンポジウム「味覚・嗅覚の分子神経機構」
    • Place of Presentation
      福岡
    • Year and Date
      2010-11-06
    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://epn.hal.kagoshima-u.ac.jp/PHYSIOL/Oral-physiol/oral-physiol.html

    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

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