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The influences of oral infections such as endodontitis on the febrile neutropenia in compromised patients

Research Project

Project/Area Number 22791836
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Conservative dentistry
Research InstitutionOkayama University

Principal Investigator

SOGA Yoshihiko  岡山大学, 岡山大学病院, 助教 (70509489)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords根尖性歯周炎 / 歯性感染巣 / 好中球減少性発熱 / 易感染 / 血液疾患
Research Abstract

I have studied the influences of oral infections such as endodontitis on the febrile neutropenia in compromised patients. We experienced a case that acute endodontitis was strongly suspected as a cause of febrile neutropenia in patients undergoing chemotherapy for hematological malignancies. Based on this case, and further studies on association between oral infections and febrile neutropenia, I suggested the significances of treatment for oral infections for compromised patients.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (31 results)

All 2012 2011 2010 Other

All Journal Article (6 results) (of which Peer Reviewed: 5 results) Presentation (24 results) Remarks (1 results)

  • [Journal Article] Histological and immunohistochemical features of gingival enlargement in a patient with AML2011

    • Author(s)
      Sonoi N, Soga Y, Maeda H, Ichimura K, Yoshino T, Aoyama K, Fujii N, Maeda Y, Tanimoto M, Logan R, Raber-Durlacher J, Takashiba S
    • Journal Title

      Odontology

      Volume: (in press)(online available) Issue: 2 Pages: 254-257

    • DOI

      10.1007/s10266-011-0051-0

    • NAID

      10030958853

    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 病院医療支援を目的とした口腔の管理学および専門診療分野の必要性-周術期医療への歯科的介入を例として-2011

    • Author(s)
      曽我賢彦
    • Journal Title

      日本口腔リハビリテーション学会雑誌

      Volume: 24(1) Pages: 1-10

    • NAID

      120004814580

    • Related Report
      2011 Final Research Report
  • [Journal Article] Bacterial substitution of coagulase-negative staphylococci for streptococci on the oral mucosa after hematopoietic cell transplantation2011

    • Author(s)
      Soga Y, Maeda Y, Ishimaru F, Tanimoto M, Maeda H, Nishimura F, Takashiba S
    • Journal Title

      Support Care Cancer

      Volume: 19(7) Pages: 995-1000

    • NAID

      120005147120

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Progress of oral care and reduction of oral mucositis-a pilot study in a hematopoietic stem cell transplantation ward.2011

    • Author(s)
      Soga Y, Sugiura Y, Takahashi K, Nishimoto H, Maeda Y, Tanimoto M, Takashiba S.
    • Journal Title

      Support Care Cancer

      Volume: 19 Pages: 303-307

    • NAID

      120005121933

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Histological and immunohistochemical features of gingival enlargement in a patient with AML

    • Author(s)
      Sonoi N, Soga Y, Maeda H, Ichimura K, Yoshino T, Aoyama K, Fujii N, Maeda Y, Tanimoto M, Logan R, Raber-Durlacher J, Takashiba S
    • Journal Title

      Odontology

      Volume: (in press)

    • NAID

      10030958853

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bacterial substitution of coagulase-negative staphylococci for streptococci on the oral mucosa after hematopoietic cell transplantation.

    • Author(s)
      Soga Y, Maeda Y, Ishimaru F, Tanimoto M, Maeda H, Nishimura F.Takashiba S.
    • Journal Title

      Support Care Cancer

      Volume: (in press)

    • NAID

      120005147120

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 造血細胞移植による口腔粘膜障害のハイリスク因子の検討2012

    • Author(s)
      佐桑奈々絵, 高橋郁名代, 村山夢乃, 西本仁美, 杉浦裕子, 曽我賢彦, 前田嘉信
    • Organizer
      第34回日本造血細胞移植学会
    • Place of Presentation
      大阪市
    • Related Report
      2011 Final Research Report
  • [Presentation] 大学病院における異職種懇話・連係の推進とその成果-歯科医師の立場から-2011

    • Author(s)
      曽我賢彦
    • Organizer
      医薬懇話会
    • Place of Presentation
      岡山市
    • Year and Date
      2011-10-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] 造血細胞移植医療における口腔内管理の意義-医歯看連携が生んだ驚くべき効果の実例から-2011

    • Author(s)
      曽我賢彦
    • Organizer
      第2回SCT Conference at Keio University Hospital
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2011-07-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Antibiotics sensitivity of bacteria on the oral mucosa after hematopoietic cell transplantation2011

    • Author(s)
      Soga Y
    • Organizer
      Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology 2011 International Symposium
    • Place of Presentation
      ギリシャ国アテネ
    • Year and Date
      2011-06-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 造血幹細胞移植における口腔内管理・ケア-歯科の立場から-2011

    • Author(s)
      曽我賢彦
    • Organizer
      第8回神奈川ハイリスク移植研究会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-05-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 医歯看連携による組織的な口腔内管理は造血細胞移植患者の口腔粘膜障害を減少させる2011

    • Author(s)
      苅田典子, 曽我賢彦, 杉浦裕子, 高橋郁名代, 西本仁美, 前田嘉信, 谷本光音, 高柴正悟
    • Organizer
      日本造血細胞移植学会
    • Place of Presentation
      松山市
    • Year and Date
      2011-03-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 造血幹細胞移植における口腔ケアチームの取り組み-歯科の立場から2011

    • Author(s)
      曽我賢彦
    • Organizer
      日本造血細胞移植学会
    • Place of Presentation
      松山市
    • Year and Date
      2011-03-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 口腔ケアの重要性-よりよいがん医療の創造のために-2011

    • Author(s)
      曽我賢彦
    • Organizer
      中国・四国広域がんプロ養成コンソーシアム平成22年度市民公開講座
    • Place of Presentation
      岡山市
    • Year and Date
      2011-02-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] がん治療における口腔内管理・ケアの意義2011

    • Author(s)
      曽我賢彦
    • Organizer
      造血細胞移植スタッフへの口腔ケアガイダンス
    • Place of Presentation
      広島県呉市
    • Year and Date
      2011-02-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 某大学病院腫瘍センターにおけるゾレドロネート(BP)投与患者の口腔に関する調査2011

    • Author(s)
      杉浦裕子, 田端雅弘, 三浦留美, 曽我賢彦, 畑中加珠, 犬飼雅子, 西本仁美, 高柴正悟, 佐々木朗
    • Organizer
      日本歯科衛生学会第6回学術大会
    • Place of Presentation
      新潟市
    • Related Report
      2011 Final Research Report
  • [Presentation] 白血病等の血液悪性疾患患者を対象とした口腔粘膜上における抗菌薬耐性遺伝子の保有状況の調査2011

    • Author(s)
      海老沼孝至, 曽我賢彦, 佐藤公麿, 苅田典子, 前田博史, 高柴正悟
    • Organizer
      第4回日本口腔検査学会総会・学術大会
    • Place of Presentation
      千葉市
    • Related Report
      2011 Final Research Report
  • [Presentation] Antibiotics sensitivity of bacteria on the oral mucosa after hematopoietic cell transplantation2011

    • Author(s)
      Soga Y
    • Organizer
      Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology 2011 International Symposium
    • Place of Presentation
      Athens, Greece
    • Related Report
      2011 Final Research Report
  • [Presentation] 医歯看連携による組織的な口腔内管理は造血細胞移植患者の口腔粘膜障害を減少させる2011

    • Author(s)
      苅田典子, 曽我賢彦, 杉浦裕子, 高橋郁名代, 西本仁美, 前田嘉信, 谷本光音, 高柴正悟
    • Organizer
      第33回日本造血細胞移植学会
    • Place of Presentation
      松山市
    • Related Report
      2011 Final Research Report
  • [Presentation] 病院医療支援を目的とした口腔の管理学および専門診療分野の必要性2010

    • Author(s)
      曽我賢彦
    • Organizer
      第24回日本顎頭蓋機能学会学術大会
    • Place of Presentation
      枚方市
    • Year and Date
      2010-10-02
    • Related Report
      2011 Final Research Report
  • [Presentation] Loop-mediated isothermal amplification(LAMP)法によるバンコマイシン耐性遺伝子(vanA、vanB)検出法の確立2010

    • Author(s)
      山部こころ, 前田博史, 曽我賢彦, 苅田典子, 高柴正悟
    • Organizer
      第31回岡山歯学会総会・学術大会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-09-26
    • Related Report
      2011 Final Research Report
  • [Presentation] 病院医療を支援する歯科医療体制の構築を目指して2010

    • Author(s)
      曽我賢彦
    • Organizer
      第31回岡山歯学会総会・学術大会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-09-26
    • Related Report
      2011 Final Research Report
  • [Presentation] 岡山大学病院腫瘍センターにおける歯科衛生士の活動-外来がん化学療法患者への取り組み-2010

    • Author(s)
      杉浦裕子, 羽川操, 三浦留美, 曽我賢彦, 畑中加珠, 高柴正悟, 佐々木朗
    • Organizer
      第31回岡山歯学会総会・学術大会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-09-26
    • Related Report
      2011 Final Research Report
  • [Presentation] 病院医療を支援する歯科医療体制の構築を目指して2010

    • Author(s)
      曽我賢彦
    • Organizer
      岡山歯学会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-09-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 病院医療支援を目的とした口腔の管理学および専門診療分野の必要性2010

    • Author(s)
      曽我賢彦
    • Organizer
      第24回日本顎頭蓋機能学会学術大会
    • Place of Presentation
      大阪府枚方市
    • Year and Date
      2010-09-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 造血器悪性疾患における感染管理における歯科からの提言-チーム医療の一員として-2010

    • Author(s)
      曽我賢彦
    • Organizer
      第24回岩手幹細胞移植研究会
    • Place of Presentation
      岩手県盛岡市
    • Year and Date
      2010-07-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] がん治療における口腔内管理・ケアの意義2010

    • Author(s)
      曽我賢彦
    • Organizer
      がん治療口腔ケアマネジメント研究会
    • Place of Presentation
      島根県出雲市
    • Year and Date
      2010-07-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 造血器悪性疾患治療における感染管理についての歯科からの提言-チーム医療の一員として-2010

    • Author(s)
      曽我賢彦
    • Organizer
      小児癌白血病研究グループフォーラム
    • Place of Presentation
      香川県丸亀市
    • Year and Date
      2010-07-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] Bacterial substitution of coagulase-negative staphylococci for streptococci on the oral mucosa after hematopoietic cell transplantation2010

    • Author(s)
      Soga Y, Maeda Y, Tanimoto M, Maeda H, Takashiba S
    • Organizer
      Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology 2010 International Symposium
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-06-25
    • Related Report
      2011 Final Research Report
  • [Presentation] Bacterial substitution of coagulase-negative staphylococci for streptococci on the oral mucosa after hematopoietic cell transplantation2010

    • Author(s)
      Soga Y, Maeda Y, Tanimoto M, Maeda H, Takashiba S.
    • Organizer
      Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology 2010 International Symposium
    • Place of Presentation
      バンクーバー
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Remarks] 報道関連情報山陽新聞記事「がん患者の口腔管理より良いがん治療に貢献」2011/2/21,バックナンバーホームページ

    • URL

      http://iryo.sanyo.oni.co.jp/hosp/h/055/c2011022110404542

    • Related Report
      2011 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

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