Calcium phosphate-alginate-calcium sulfate composite for bone regeneration

• Project/Area Number: 22791859
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Prosthetic dentistry
• Research Institution: Tohoku University
• Principal Investigator: FUJI Takeshi 東北大学, 大学院・歯学研究科, 助教 (20549323)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: アルギン酸 / リン酸カルシウム / 硫酸カルシウム / 骨再生 / 骨再建 / 骨芽細胞

Research Abstract

We established a method and conditions to prepare alginate/calcium sulfate composites contain calcium phosphate most efficiently. This composites keeps osteogenic ability from calcium phosphate and its form. The results suggest that this composites has potential to provide a better scaffold in bone defect regardless its size or shape.