Development of poly(P) adsorbed Electrical polarized hydroxyapatite artificial bone.

• Project/Area Number: 22791889
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Prosthetic dentistry
• Research Institution: Hiroshima University
• Principal Investigator: DOI Kazuya 広島大学 (80444686)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 分極アパタイト / 人工骨 / 再生医療

Research Abstract

The purpose of this study is to evaluate the bone formation ability of poly(P) adsorbed Electrical polarized hydroxyapatite artificial bone. This study indicated that co-application of Electrical polarized hydroxyapatite and poly(P) may provide enhanced cell differentiation and the mineralization in vitro and bone formation in vivo. It is anticipated that a combined application of Electrical polarized hydroxyapatite and poly(P) can provide a novel method for bone regeneration in clinical use.

Research Products

• [Journal Article] rative evaluation of bone regeneration using spherical and irregularly shaped granules of interconnected porous hydroxylapatite (2011)
  • Author(s): Kubo T, Doi K, Hayashi K, Morita K, Matsuura A, Teixeira ER, Akagawa Y. Compa
  • Journal Title: A beagle dog study. J Prosthodont Res Volume: 55 Pages: 104-9
  • Peer Reviewed
• [Presentation] 連通多孔性ハイドロキシアパタイトによる骨再建部位におけるオッセオインテグレーションの様相 (2011)
  • Author(s): 梶原志穂, 土井一矢, 久保隆靖, 森田晃司, 赤川安正
  • Organizer: 「第50回広島県歯科医学会」併催「第95回広島大学歯学会」
  • Place of Presentation: 広島
  • Year and Date: 2011-11-13
• [Presentation] The Aspects of Osseointegration of The Imlants Placed in The Reconstructed Bone by Using Interconnected Porous Calcium Hyroxyapatite (2011)
  • Author(s): KAJIHARA SHIHO, KAZUYA DOI et al.
  • Organizer: 4th Hiroshima Conference on Education and Science in Dentistry
  • Place of Presentation: Hiroshima(Japan)
  • Year and Date: 2011-10-09
• [Presentation] 連通多孔性ハイドロキシアパタイトを用いた骨再建部位におけるオッセオインテグレーションの様相 (2011)
  • Author(s): 梶原志穂, 土井一矢ら
  • Organizer: 第41回日本航空インプラント学会学術大会
  • Place of Presentation: 名古屋市
  • Year and Date: 2011-09-17
• [Presentation] The Aspects of Osseointegration of The Implants Placed in The Reconstructed Bone by Using Interconnected Porous Calcium Hydroxyapatite (2011)
  • Author(s): KAJIHARA SHIHO, KAZUYA DOI et al
  • Organizer: 4th Meeting of the International College of Prosthodontists
  • Place of Presentation: USA
  • Year and Date: 2011-09-11
• [Presentation] The Aspects of Osseointegration of The Implants Placed in The Reconstructed Bone by Using Interconnected Porous Calcium Hydroxyapatite (2011)
  • Author(s): KAJIHARA S, DOI K, OUE H, MATSUURA A, MORITA K, TAKESHITA R, ASAMORI C, AKAGAWA Y
  • Organizer: International College of Prosthodontists
  • Place of Presentation: Hawaii(USA)
• [Presentation] 連通多孔性ハイドロキシアパタイトを用いた骨再建部位におけるオッセオインテグレーションの様相 (2011)
  • Author(s): 梶原志穂, 土井一矢, 久保隆靖, 森田晃司, 赤川安正
  • Organizer: 日本口腔インプラント学会
  • Place of Presentation: 名古屋
• [Presentation] The Aspects of Osseointegration of The Implants Placed in The Reconstructed Bone by Using Interconnected Porous Calcium Hydroxyapatite (2011)
  • Author(s): KAJIHARA S,DOI K, KUBO T, OUE H, MATSUURA A, MORITA K, TAKESHITA R. ASAMORI C, AKAGAWA Y
  • Organizer: 4th Hiroshima Conference on Education and Science in Dentistry
  • Place of Presentation: Hiroshima