| Project/Area Number |
22791908
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Kanagawa Dental College |
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Principal Investigator |
HORI Norio 神奈川歯科大学, 歯学部, 非常勤講師 (20386832)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | チタン / 表面特性 / インプラント / 細胞接着能 / タンパク吸着能 / バイオロジカルエイジング / バイオマテリアル / インプラント-骨接触率 / 生体材料 / 表面性状 / エイジング / 表面加工 / オッセオインテグレーション |
|---|
| Research Abstract |
Possible changes in biological potential of titanium(Ti) over time have never been addressed, with a presumption that titanium surfaces are stable in biological property, particularly osseointegration capability. The purpose of this research was to test a hypothesis that protein adsorption capacity and cell attractiveness of Ti, which are critical to the process of osseointegration, changes over time before its use. Degrading trend of protein adsorption capacity and osteoblast attractiveness of Ti surfaces during 4 weeks of storage after processing was remarkable. We postulate that immediate action needs to be taken to explore this phenomenon for possible substantial commercial, scientific and research impacts in the field.
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