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Changes in bone quality associated with the newly surface treatment implant using bioelement in the ovariectomised rat.

Research Project

Project/Area Number 22791942
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Dental engineering/Regenerative dentistry
Research InstitutionNihon University

Principal Investigator

NAKADA Hiroshi  日本大学, 松戸歯学部, 講師 (10349970)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords歯学 / 細胞・組織 / 骨 / 動物 / インプラント / 動物実験 / ミネラル / Miccro-CT / ラット / 骨塩量 / 骨体積
Research Abstract

To achieve the long-term retention and stability of implants under such conditions, the quality of newly formed bone around implants is important. There have been many studies reporting that new bone formed around implants is spongy bone. However, although the morphology is reportedly like spongy bone, it is difficult to discriminate whether the bone quality of new bone is mature like cortical bone, or immature, being similar to spongy bone, osteoid, or cartilaginous bone; therefore, evaluation of the bone quality is required. In this study, differences in the bone quality between new bone and cortical bone formed around implants were investigated using Micro-XRD and EDX.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (26 results)

All 2012 2011 2010

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (11 results)

  • [Journal Article] 低ミネラル食を摂取させた卵巣摘出ラットの大腿骨骨幹端部における骨変化2012

    • Author(s)
      中田浩史,鈴木静夏,渡辺丈紘,寒河江登志朗,谷本安浩,河相安彦.
    • Journal Title

      日本補綴歯科学会誌

      Volume: 4巻 Pages: 76-84

    • NAID

      10030447539

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of the Quality of Newly Formed Bone around Titanium Alloy Implants by using X-ray Photoelectron Spectroscopy.2012

    • Author(s)
      Hiroshi Nakada, Toshiro Sakae, Yasuhiro Tanimoto, Mari Teranishi, Takao Kato, Takehiro Watanabe, Hiroyuki Saeki, Yasuhiko Kawai and Racquel Z. Legeros.
    • Journal Title

      International Journal of Biomaterials

      Volume: 61 Pages: 1-7

    • DOI

      10.1155/2012/615018

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bone quality of the femoral mid-shaft of ovariectomized rats fed a low-mineral diet.2012

    • Author(s)
      Shizuka Suzuki, Hiroshi Nakada, Toshiro.Sakae, Yasuhiro Tanimoto, Yasuhiko Kawai and Racquel Z. Legeros.
    • Journal Title

      Journal of HardTissue Biology

      Volume: 21 Pages: 245-256

    • NAID

      40019716510

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in bone quality of the femoral diaphysis induced by high-level fluorine ingestion in ovariectomized rats2012

    • Author(s)
      Hiroshi Nakada, Toshiro Sakae, Mari Teranishi, Takao Kato, Takehiro Watanabe, Takahiro Takahashi, Yasuhiko Kawai and Racquel Z. LeGeros.
    • Journal Title

      Key Engineering Materials

      Pages: 341-344

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison between the lateral and medial femur in low-mineral- diet-fed ovariectomized rats using Raman spectral analysis.2012

    • Author(s)
      Toshiro Sakae, Hiroshi Nakada, MariTeranishi, Takao Kato, Shizuka Suzuki, Akira Yanagawa, Norio Yasuda, Shukichi Ochiai, Nobby Kitagawa, Yasuhiko Kawai and Racquel Z. LeGeros.
    • Journal Title

      Key EngineeringMaterials

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in bone quality of the femoral diaphysis induced by high-level fluorine ingestion in ovariectomized rats2012

    • Author(s)
      Nakada H, Sakae T, Teranishi M, Kato T, Watanabe T, Takahashi T, Kawai Y, LeGeros R.Z.
    • Journal Title

      Key Engineering Materials

      Volume: 529-530 Pages: 341-344

    • DOI

      10.4028/www.scientific.net/kem.529-530.341

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison between the lateral and medial femur in low-mineral- diet-fed ovariectomized rats using Raman spectral analysis.2012

    • Author(s)
      Sakae T, Nakada H, Teranishi M, Kato T, Suzuki S, Yanagawa A, Yasuda N, Ochiai S, Kitagawa N, Kawai Y, LeGerosR.Z.
    • Journal Title

      Key Engineering Materials

      Volume: 529-530 Pages: 337-340

    • DOI

      10.4028/www.scientific.net/kem.529-530.337

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bone quality of the femoral mid-shaft of ovariectomized rats fed a low-mineral diet2012

    • Author(s)
      Suzuki S, Nakada H, Sakae T, Tanimoto Y, Kawai Y, Legeros R.Z.
    • Journal Title

      Journal of Hard Tissue Biology

      Volume: 21 Pages: 245-256

    • NAID

      40019716510

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 低ミネラル食を摂取させた卵巣摘出ラットの大腿骨骨幹端部における骨変化2012

    • Author(s)
      中田浩史, 鈴木静夏, 他
    • Journal Title

      日本補綴歯科学会誌

      Volume: 4 Pages: 76-84

    • NAID

      10030447539

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 卵巣摘出したラットが摂取するミネラルの違いによる大腿骨骨幹部の骨質変化-Micro-CTによる観察-.2011

    • Author(s)
      中田浩史,鈴木静夏,渡辺丈紘,寒河江登志朗,谷本安浩,久保山昇,中臺麻美,寺西真理,櫻井甫,木本統,矢崎貴啓,林幸男,郡司敦子,佐伯啓行,加藤仁夫,河相安彦.
    • Journal Title

      日大口腔科学

      Volume: 37 Pages: 13-21

    • NAID

      40019031450

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative and qualitative analyses oflow-mineral-diet ovariectomised rat femora using microscopic computed tomography.2011

    • Author(s)
      Hiroshi Nakada, Shizuka Suzuki,Toshiro Sakae, Yasuhiro Tanimoto, Noboru Kuboyama, Mari Teranishi, Takao Kato, Takehiro Watanabe, Hiromi Kimura-Suda, Racquel Z. LeGeros, and Yasuhiko Kawai.
    • Journal Title

      Journal of Hard TissueBiology

      Volume: 20 Pages: 107-114

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 卵巣摘出したラットが摂取するミネラルの違いによる大腿骨骨幹部の骨質変化-Micro-CTによる観察-2011

    • Author(s)
      中田浩史, 鈴木静夏, 他
    • Journal Title

      日大口腔科学

      Volume: 37 Pages: 13-21

    • NAID

      40019031450

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative and qualitative analyses of low-mineral-diet ovariectomised rat femora using microscopic computed tomography2011

    • Author(s)
      Nakada H, Suzuki S, et al
    • Journal Title

      Journal of Hard Tissue Biology

      Volume: 20 Pages: 107-117

    • NAID

      130004480516

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in bone quality associated with the mineralization of new bone formed around implants ?Using XPS, polarized nicroscopy, and FTIR imaging-.2010

    • Author(s)
      Hiroshi Nakada, Yasuko Numata, Toshiro Sakae, Hiromi Kimura-Suda, Yasuhiro Tanimoto, Hiroyuki Saeki, Mari Teranishi, Takao Kato, Racquel Z. LeGeros.
    • Journal Title

      Journal of Hard Tissue Biology

      Volume: 19 Pages: 101-110

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in Bone Quality Associated with the Mineralization of New Bone Formed Around Implants-Using XPS, Polarized Microscopy, and FTIR imaging-2010

    • Author(s)
      Hiroshi Nakada, Yasuko Numata, Toshiro Sakae, Hiromi Kimura-Suda, Yasuhiro Tanimoto, Hiroyuki Saeki, Mari Teranishi, Takao Tato, Racquel Z.LeGeros
    • Journal Title

      Journal of Hard Tissue Biology

      Volume: 19 Pages: 101-110

    • NAID

      10027421928

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 低ミネラル食を与えた卵巣摘出ラットのインプラント周囲の新生骨の形成に関する検討.2012

    • Author(s)
      渡辺丈紘、中田浩史、寒河江登志朗、鈴木静夏、河相安彦.
    • Organizer
      第121回日本補綴歯科学会学術大会
    • Place of Presentation
      神奈川県民ホール、神奈川.
    • Year and Date
      2012-05-27
    • Related Report
      2012 Final Research Report
  • [Presentation] Comparison between the lateral and medial femur in low-mineral- diet-fed ovariectomized rats using Raman spectral analysis.2012

    • Author(s)
      Sakae T, Nakada H, Teranishi M, Kato T, Suzuki S, Yanagawa A, Yasuda N, Ochiai S, Kitagawa N, Kawai Y, LeGerosR.Z.
    • Organizer
      24th International Symposium of Ceramics in Medicine
    • Place of Presentation
      Centennial Hall Kyushu University School of Medicine Fukuoka (Japan)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Changes in bone quality of the femoral diaphysis induced by high-level fluorine ingestion in ovariectomized rats2012

    • Author(s)
      Nakada H, Sakae T, Teranishi M, Kato T, Watanabe T, Takahashi T, Kawai Y, LeGeros R.Z.
    • Organizer
      24th International Symposium of Ceramics in Medicine
    • Place of Presentation
      Centennial Hall Kyushu University School of Medicine Fukuoka (Japan)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 有床義歯補綴学のWebClassを用いた学習支援2012

    • Author(s)
      大久保昌和、宗 邦雄、石井智浩、矢崎貴啓、中田浩史、飯島守雄、河相安彦
    • Organizer
      第12回日本大学口腔科学会学術大会
    • Place of Presentation
      日本大学松戸歯学部 (千葉)
    • Related Report
      2012 Annual Research Report
  • [Presentation] インプラント周囲に形成される新生骨の石灰化に関する検討2012

    • Author(s)
      渡辺丈紘、中田浩史、寒河江登志朗、鈴木静夏、高橋卓裕、谷本安浩、加藤仁夫、河相安彦
    • Organizer
      第12回日本大学口腔科学会学術大会
    • Place of Presentation
      日本大学松戸歯学部 (千葉)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 低ミネラル食を与えた卵巣摘出ラットのインプラント周囲の新生骨の形成に関する検討2012

    • Author(s)
      渡辺丈紘、中田浩史、寒河江登志朗、鈴木静夏、河相安彦
    • Organizer
      第121回日本補綴歯科学会学術大会
    • Place of Presentation
      神奈川県民ホール (神奈川)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 低ミネラル食を与えた卵巣摘出ラットの大腿骨をMicro-CTによる定性と定量分析.2011

    • Author(s)
      鈴木静夏、中田浩史、林幸男、郡司敦子、河相安彦.
    • Organizer
      第120回日本補綴歯科学会
    • Place of Presentation
      広島国際会議場、広島.
    • Year and Date
      2011-05-21
    • Related Report
      2012 Final Research Report
  • [Presentation] 低ミネラル食を与えた卵巣摘出ラットの大腿骨をMicro-CTによる定性と定量分析2011

    • Author(s)
      鈴木静夏、中田浩史, 他
    • Organizer
      日本補綴歯科学会
    • Place of Presentation
      広島(国際会議場)
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 卵巣摘出したラットに低ミネラル食を与えた際の大腿骨の骨質変化2011

    • Author(s)
      鈴木静夏、中田浩史、寺西真理、加藤仁夫、河相安彦.
    • Organizer
      日本口腔インプラント学会28回九州支部学術大会
    • Place of Presentation
      かごしま県民交流センター、鹿児島.
    • Year and Date
      2011-01-22
    • Related Report
      2012 Final Research Report
  • [Presentation] 卵巣摘出したラットに低ミネラル食を与えた際の大腿骨の骨質変化2011

    • Author(s)
      鈴木静夏、中田浩史、寺西真理、加藤仁夫、河相安彦
    • Organizer
      日本口腔インプラント学会 28回九州支部学術大会
    • Place of Presentation
      鹿児島
    • Year and Date
      2011-01-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] X-ray PhaseContrast Imaging of Dental Tissues.2010

    • Author(s)
      T. SAKAE, H. OKADA, H. NAKADA, K.SUZUKI, and H. YAMAMOTO.
    • Organizer
      The 58th AnnualMeeting of Japanese Association forDental Research
    • Place of Presentation
      Kyushu Dental College,Fukuoka.
    • Year and Date
      2010-11-20
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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