Functional analysis of the bone differentiation from isolated mesenchymal stem cell from the apical pulp of human teeth
Project/Area Number |
22791954
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Surgical dentistry
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Research Institution | University of Tsukuba |
Principal Investigator |
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Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 骨分化能 / 間葉系幹細胞(MSCs) / 骨折モデルマウス / 智歯歯髄 / CD349 / 歯由来間葉系細胞 / 根尖部歯髄組織 / Aldehyde dehydrogenase活性 / 智歯 |
Research Abstract |
The purpose of this study was to analyze the function of the bone differentiation for isolated mesenchymal stem cells (MSCs) from the apical pulp of human teeth. Function of bone differentiation was higher in the stage of completed root formation than other stages in vitro. The CD349 (+) MSCs which were isolated from CD349 marker expressing the function of bone formation were excellent for bone differentiation in vivo.
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Report
(3 results)
Research Products
(4 results)
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[Presentation] ヒト智歯歯髄由来間葉系幹細胞の骨分化能に対する機能解析2011
Author(s)
山縣憲司, 長野真澄, 木村健一, 菊地豪, 佐々木裕芳, 瀬戸佳穂里, 内田文彦,柳川徹, 鬼澤浩司郎, 武川寛樹, 大根田修
Place of Presentation
大阪
Year and Date
2011-10-22
Related Report
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