The sensibility of chemoradiotherapy in oral squamous cell carcinoma cells transfected with HPV-E6/ E7 gene
| Project/Area Number |
22791974
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
ISHIBASHI Miki 大阪大学, 大学院・歯学研究科, 招聘教員 (40412051)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 口腔癌 / HPV / 治療感受性 / 分子生物学 / 口腔扁平上皮癌 / 放射線化学療法 / 口腔多発癌 |
|---|
| Research Abstract |
The aim of this study was to clarify the sensibility of chemoradiotherapy in HPV-positive oral squamous cell carcinomas. Briefly, we evaluated the frequency of HPV infection in oral lesions, and p16^<INK4a>、p53、CD4、CD8、CD68、CD1a Ctr1 were immunohistochemically examined in order to evaluate its correlation with HPV infection. In oral lesions, the total HPV-positive rate was 22. 4%. We did not find significant correlation immunohistochemically with HPV infection. The sensibility of chemoradiotherapy in HPV-positive cases depend on, suggesting the involvement of other factors.
|
Report
(3 results)
Research Products
(14 results)
-
-
-
-
-
-
-
-
-
-
[Presentation] 口唇裂・口蓋裂に伴う上顎骨劣成長に対する上顎骨前方部骨延長術(MASDO)の検討2011
Author(s)
原田丈司, 相川友直, 石濱孝二, 樋口将隆, 牛村彩子, 田中晋, 石橋美樹, 永谷俊介, 奥野恵実, 山本奈穂, 木田久美子, 田中輝, 程壮樹, 飯田征二, 古郷幹彦
Organizer
第21回日本顎変形症学会総会
Place of Presentation
東京
Related Report
-
-
-
-
